NCT01298440

Brief Summary

Retinal blood flow velocity is affected by Bevacizump intravitreal injection. This effect is correlated to treatment success.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2008

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2008

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2008

Completed
2.7 years until next milestone

First Submitted

Initial submission to the registry

February 16, 2011

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 17, 2011

Completed
Last Updated

February 17, 2011

Status Verified

February 1, 2011

Enrollment Period

5 months

First QC Date

February 16, 2011

Last Update Submit

February 16, 2011

Conditions

Outcome Measures

Primary Outcomes (1)

  • Blood flow velocity change

    1 day following injection

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with choroidal neovascularization (CNV)

You may qualify if:

  • Patients with CNV receiving Bevacizumab intravitreal injection

You may not qualify if:

  • Candidates in whom the retina could not be seen clearly because of media opacity or a poorly dilating pupil

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tel aviv sourasky medical center

Tel Aviv, 64239, Israel

Location

Related Publications (1)

  • Burgansky-Eliash Z, Lowenstein A, Neuderfer M, Kesler A, Barash H, Nelson DA, Grinvald A, Barak A. The correlation between retinal blood flow velocity measured by the retinal function imager and various physiological parameters. Ophthalmic Surg Lasers Imaging Retina. 2013 Jan-Feb;44(1):51-8. doi: 10.3928/23258160-20121221-13.

MeSH Terms

Conditions

Choroidal Neovascularization

Condition Hierarchy (Ancestors)

Choroid DiseasesUveal DiseasesEye DiseasesNeovascularization, PathologicMetaplasiaPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Adiel Barak, MD

    Tel aviv university Sackler school of medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

February 16, 2011

First Posted

February 17, 2011

Study Start

January 1, 2008

Primary Completion

June 1, 2008

Study Completion

June 1, 2008

Last Updated

February 17, 2011

Record last verified: 2011-02

Locations