The Association Between Religious Origin and Age, and Vitamin B12 and Folic Acid Plasma Levels in Non Jewish Population in Western Galilee

NCT01297361 | Completed

• 1 other identifier: K.Hassan
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

Vitamin B12 deficiency is more widespread in the population than has been assumed so far. Since a deficiency in this vitamin can lead to irreversible neurological damage, early diagnosis is essential. Vitamin B12 is synthesized exclusively in micro-organisms, and in humans it is an essential component in methyl group transfer and cell division. The vitamin is crucially involved in the proliferation, maturation, and regeneration of neural cells. In combination with folic acid, as an enzymatic essential cofactor in the metabolism of homocysteine, vitamin B12 maintains low homocysteine levels. The aim of the present study is to investigate the relationship between religious origin and age, and Vitamin B12 and Folic acid plasma levels in non Jewish population in Western Galilee. The investigators assumption is that the results of the study will contribute to early detection and treatment of Vitamin B12 and Folic acid deficiencies in order to prevent long term complications.

Conditions

Vitamin B12 Deficiency; Folic Acid Deficiency

Outcome Measures

Primary Outcomes (4)

• The number of participants of each religious origin group with folic acid deficiency

  The association between religious origin (Christians,Muslims and Druze) and folic acid plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of this vitamin will be treated accordingly.

  10 months

• The number of participants of each age group with Vitamin B12 deficiency

  The association between age groups (18-40, 41-65 and above 65 years old) and Vitamin B12 plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of this vitamin will be treated accordingly

  10 months

• The number of participants of each age group with folic acid deficiency

  The association between age groups (18-40, 41-65 and above 65 years old) and folic acid plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of this vitamin will be treated accordingly

  10 months

• The number of participants of each religious origin group with Vitamin B12 deficiency

  The association between religious origin (Cristians, Muslims and Druze) and Vitamin B12 plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of these vitamins will be treated accordingly.

  10 months

Study Arms (1)

Plasma Vitamin B12 and Folic acid levels

OTHER

Blood sample was drawn

Other: Blood Sample

Interventions

Blood Sample OTHER

Blood sampling for diagnosis of vitamins deficiencies

Plasma Vitamin B12 and Folic acid levels

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age:18 and older
• Able to understand and to sign informed consent

You may not qualify if:

• Gastrointistinal Diseases
• Malignancy
• Psychiatric disorders
• Pregnancy
• Treatment with Vit B12 or Folic acid

Sponsors & Collaborators

• Meir Medical Center: lead

Study Sites (1)

Clalit health services

Kfar Yassif, 24908, Israel

Location

MeSH Terms

Conditions

Vitamin B 12 Deficiency; Folic Acid Deficiency

Interventions

Blood Specimen Collection

Condition Hierarchy (Ancestors)

Vitamin B Deficiency; Avitaminosis; Deficiency Diseases; Malnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 2, 2011
• First Posted: February 16, 2011
• Study Start: February 1, 2011
• Primary Completion: November 1, 2011
• Study Completion: August 1, 2012
• Last Updated: April 23, 2013

Record last verified: 2012-03

Locations

IL (1)