Indicators of Operative and Postoperative Complications in Patients Operated for Hip Fracture

NCT01294930 | Completed

• 1 other identifier: IOPC
• Study Type: observational
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

Patients operated for hip fractures are older and have several conditions that have negative influences on the perioperative and postoperative prognosis. Hip fractures can also be painful, which is stressful for the physiology of the patient. Many old patients have received to little fluid intake. They often have diuretic therapy, which even worsens dehydration/hypovolemia. Some patients have to wait several days for surgery. Several studies have shown a high degree of complications and an increased mortality in this patient group. Early preoperative optimization can improve the outcome. The available methods for optimization of the patient are complicated and time consuming. The investigators wish with this study to try new approaches to find which patients still are dehydrated when they come to the operation ward. The aim is to measure the color and density of the urine as well as to register the the variability in the plethysmographic curve before spinal anaesthesia. These results will be compared to circulatory instability during and after surgery as well as to postoperative complications.

Conditions

Hip Fracture

Keywords

hip fracture; mortality; complications

Outcome Measures

Primary Outcomes (1)

• mortality

  30-day mortality related to indices of dehydration (urine and pulse oximetry)

  30 days

Secondary Outcomes (1)

• operative and postoperative complications

  3 days

Study Arms (1)

hip fracture

Patients operated for hip fracture, giving informed consent

Other: Urine density

Interventions

Urine density OTHER

measurement of urine color, density and plethysmographic variability index before and during surgery.

Also known as: - Urine color, - Urine density, - Plethysmographic variabilty

hip fracture

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with hip fracture operated at the hospital in Norrkoeping

You may qualify if:

• patients with hip fracture
• operation for the hip fracture
• informed consent

You may not qualify if:

• patients not giving consent
• patients not being able to understand information

Sponsors & Collaborators

• University Hospital, Linkoeping: lead
• Vrinnevi Hospital: collaborator

Study Sites (1)

Anaesthesia dept, Vrinnevisjukhuset

Norrköping, Norrkoeping, Sweden

Location

Related Publications (1)

• Ylinenvaara SI, Elisson O, Berg K, Zdolsek JH, Krook H, Hahn RG. Preoperative urine-specific gravity and the incidence of complications after hip fracture surgery: A prospective, observational study. Eur J Anaesthesiol. 2014 Feb;31(2):85-90. doi: 10.1097/01.EJA.0000435057.72303.0e.

  PMID: 24145802 DERIVED

Biospecimen

Retention: NONE RETAINED

Urine

MeSH Terms

Conditions

Hip Fractures

Condition Hierarchy (Ancestors)

Femoral Fractures; Fractures, Bone; Wounds and Injuries; Hip Injuries; Leg Injuries

Study Officials

• Robert Hahn, MD PhD Prof

  University Hospital, Linkoeping

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD, PhD

Study Record Dates

• First Submitted: February 11, 2011
• First Posted: February 14, 2011
• Study Start: January 1, 2011
• Primary Completion: July 1, 2012
• Study Completion: July 1, 2012
• Last Updated: February 21, 2013

Record last verified: 2013-02

Locations

SE (1)