Quantifying and Understanding the Signs and Symptoms of Fever

NCT01287143 | Terminated

• 2 other identifiers: 11008311-CC-0083
• Study Type: observational
• Target: 99
• Locations: 1 country
• Sites: 1

Brief Summary

Background: \- Fever is a common symptom of illness, but it can involve many signs (a signal that something is not right in the body that can be seen by others, such as vomiting) and symptoms (a signal that something is not right in the body that are felt only by the person, such as pain) that may differ depending on the type of illness involved. Researchers are interested in studying individuals who have a fever to examine how often these signs and symptoms are experienced by patients. Objectives: \- To identify and evaluate the signs and symptoms of fever and examine their frequency in individuals who have fever. Eligibility: \- Individuals at least 8 years of age who are admitted to the NIH Clinical Center and have a fever (body temperature of at least 38 degrees Celsius/100.4 degrees Fahrenheit). Design:

• Participants will be screened upon admission to the NIH Clinical Center.
• Researchers will review the Clinical Center admission records.
• Participants will complete a 15- to 20-minute survey with questions about how they are feeling and what symptoms they have experienced before, during and after an episode of fever.

Conditions

Fever

Keywords

Fever; Signs and Symptoms; Febrile Assessment Tool (FAST)

Outcome Measures

Primary Outcomes (1)

• Symptoms of fever

  Throughout in patient admission

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult and pediatric medical-surgical patients hospitalized in the Clinical Center, NIH admitted to 3NE (oncology/ transplant), 3NW (surgical oncology) and 1NW (pediatrics).
• Oriented to person, time and place at time of interview
• Active fever (body temperature greater than or equal to 38.0 Celsius), treated or untreated, within the last 12 hours.
• Willingness to participate in a short interview (15-20 minutes) about their symptoms
• Understands and speaks English
• Age 8 years and older
• Adult (18 years of age or greater) medical-surgical patients hospitalized at the Clinical Center and admitted to 3NW.
• Oriented to person, time and place at time of admission
• Willingness to be asked about their symptoms of fever during vital signs assessment
• Understands and speaks English
• Inpatients admitted to the Clinical Center
• Age 8 years and older

Sponsors & Collaborators

• National Institutes of Health Clinical Center (CC): lead

Study Sites (1)

National Institutes of Health Clinical Center, 9000 Rockville Pike

Bethesda, Maryland, 20892, United States

Location

Related Publications (4)

• Laupland KB. Fever in the critically ill medical patient. Crit Care Med. 2009 Jul;37(7 Suppl):S273-8. doi: 10.1097/CCM.0b013e3181aa6117.

  PMID: 19535958 BACKGROUND

• Chesnutt BK, Zamora MR, Kleinpell RM. Blood cultures for febrile patients in the acute care setting: too quick on the draw? J Am Acad Nurse Pract. 2008 Nov;20(11):539-46. doi: 10.1111/j.1745-7599.2008.00356.x.

  PMID: 19128337 BACKGROUND

• Bor DH, Makadon HJ, Friedland G, Dasse P, Komaroff AL, Aronson MD. Fever in hospitalized medical patients: characteristics and significance. J Gen Intern Med. 1988 Mar-Apr;3(2):119-25. doi: 10.1007/BF02596115.

  PMID: 3357068 BACKGROUND

• Ames NJ, Powers JH, Ranucci A, Gartrell K, Yang L, VanRaden M, Leidy NK, Wallen GR. A systematic approach for studying the signs and symptoms of fever in adult patients: the fever assessment tool (FAST). Health Qual Life Outcomes. 2017 Apr 27;15(1):84. doi: 10.1186/s12955-017-0644-6.

  PMID: 28449675 DERIVED

MeSH Terms

Conditions

Fever; Signs and Symptoms

Condition Hierarchy (Ancestors)

Body Temperature Changes; Pathological Conditions, Signs and Symptoms

Study Officials

• Nancy Ames, R.N.

  National Institutes of Health Clinical Center (CC)

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: NIH
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 29, 2011
• First Posted: February 1, 2011
• Study Start: January 13, 2011
• Study Completion: August 9, 2017
• Last Updated: October 6, 2017

Record last verified: 2017-08-09

Locations

US (1)