NCT01274468

Brief Summary

The aim of this study is to determine if DCAMLK1 can be measured in the endobronchial biopsy specimens and bronchial washings from patients with lung cancer.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Aug 2009

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2009

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

May 20, 2010

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2010

Completed
5 months until next milestone

First Posted

Study publicly available on registry

January 11, 2011

Completed
Last Updated

August 10, 2012

Status Verified

August 1, 2012

Enrollment Period

1 year

First QC Date

May 20, 2010

Last Update Submit

August 8, 2012

Conditions

Lung Cancer

Outcome Measures

Primary Outcomes (1)

  • Identification of DCAMLK1 in BAL and lung biopsy specimens.

    After collection and analysis of specimens.

Eligibility Criteria

Age45 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Ten patients with an expected age \>45 years

You may qualify if:

  • abnormality on chest x-ray that requires diagnosis and physically capable of undergoing bronchoscopy

You may not qualify if:

  • \<45 years
  • Patients with severe abnormalities in blood gases and/or a coagulopathy will be excluded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Veterans Affairs Medical Center

Oklahoma City, Oklahoma, 73104, United States

Location

Related Publications (1)

  • Humphries A, Wright NA. Colonic crypt organization and tumorigenesis. Nat Rev Cancer. 2008 Jun;8(6):415-24. doi: 10.1038/nrc2392. Epub 2008 May 15.

    PMID: 18480839BACKGROUND

Biospecimen

Retention: SAMPLES WITHOUT DNA

Lung biopsy

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Study Officials

  • Gary T Kinasewitz, MD

    OU Health Sciences Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 20, 2010

First Posted

January 11, 2011

Study Start

August 1, 2009

Primary Completion

August 1, 2010

Study Completion

August 1, 2010

Last Updated

August 10, 2012

Record last verified: 2012-08

Locations

US(1)