Trials Sponsors Conditions Drugs Pricing

Conditions

HIV Infection Young Adult

Keywords

teenagers to adult transitioncomparison

Outcome Measures

Primary Outcomes (1)

Immuno virological and clinical prognosis: HIV RNA <50c/mL, CD4 cells count>500 cells/mL, vital status, CDC stage
at inclusion and annually up to 06 years follow-up

Secondary Outcomes (4)

Professional and schooling integration, social life:marital status, type of accommodation, education level, type and age at first employment
at inclusion and annually up to 6 years follow up
sexuality, sexual risk behaviour: age at first intercourse, condom use at first, last sexual intercourse, and during last year, unplanned pregnancy, interruption of pregnancy
at inclusion and annually up to 6 year follow-up
metabolic and cardiovascular abnormalities: abnormalities in glucose tolerance and insulino-resistance, dyslipidemia, lipodystrophy, adipocyte dysfunction, atherosclerosis,dysfunction, median of intima media thickness and pulse wave velocity
at inclusion and after 3 years follow-up
Lymphocyte phenotype and functional capacity of T lymphocyte: description of dysfunctional CMV-specific T cell, T cell responses measured at inclusion, and their evolution during follow-up
at inclusion and after 3 years follow-up

Study Arms (2)

HIV infected

OTHER

young adult infected by HIV

Biological: blood sampling, specific biological exams and biobank and self administered questionnaires

HIV uninfected

OTHER

a control group of HIV uninfected young adult will be included for comparison in physiopathological module (metabolic, cardiovascular, and immunological)

Biological: blood sampling, specific biological exams and biobank and self administered questionnaires

Interventions

blood sampling, specific biological exams and biobank and self administered questionnairesBiological

HIV INFECTION at inclusion and annually up to 06 years follow-up 1. clinical and therapeutic evaluation by physician 2. biological: blood sampling, specific biological exams and biobank 3. self administered questionnaires In the physiopathological module: at inclusion and after 3 years follow up: OGTT, CT Scan, Dexa Scan, cardiovascular explorations (carotid intima media thickness, pulse wave velocity, transthoracic echocardiography) HIV UNINFECTED at inclusion and after 3 years follow up 1. clinical evaluation by physician 2. biological: blood sampling, specific biological exams and biobank 3. self administered questionnaires

HIV infectedHIV uninfected

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 25 Years

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

Age ≥ 18 and \< 25 years
Able to give written consent

Sponsors & Collaborators

French National Agency for Research on AIDS and Viral Hepatitis
Governmentlead

Study Sites (1)

Hôpitaux (voir liste jointe)

De France, France

MeSH Terms

Conditions

HIV Infections

Interventions

Blood Specimen CollectionBiological Specimen Banks

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital Diseases

Study Officials

Hugues Aumaitre
Perpignan Hospital Center
PRINCIPAL INVESTIGATOR
Eric Froguel
Hopital de Lagny
PRINCIPAL INVESTIGATOR
Michèle Bentata
Hopital Avicenne
PRINCIPAL INVESTIGATOR
Philippe Genet
Hopital Argenteuil
PRINCIPAL INVESTIGATOR

Enrollment

469 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NON RANDOMIZED
Masking: NONE
Purpose: OTHER
Intervention Model: PARALLEL
Sponsor Type: OTHER GOV
Responsible Party: SPONSOR

Study Record Dates

First Submitted

September 17, 2010

First Posted

January 4, 2011

Study Start

June 2010

Date type not reported

This date has not been verified as actual or estimated.

Cohort of Young Adults Infected With HIV Since Birth or During Childhood

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (2)

HIV infected

HIV uninfected

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Links

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Intervention Hierarchy (Ancestors)

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (2)

HIV infected

HIV uninfected

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Links

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Intervention Hierarchy (Ancestors)

Source record

Locations