Red Wine and Ageing and Atherosclerosis
The Red Wine Project: a Study of Ageing Indexes and Prevalence of Atherosclerosis in Regular Red Wine Consumers Versus Abstainers
1 other identifier
observational
200
1 country
1
Brief Summary
The investigators will evaluate 100 regular red wine consumer men and 100 abstainers men from 50 years-old to 70 years-old by coronary risk prevalence, mood status, anthropometric measures, daily caloric ingest, lipid profile, carotid intimal media thickness, brachial flow mediate dilatation, coronary tomographic angiography and leucocyte telomere length. The sample size has been calculated expecting that regular red wine ingestion would lead to a five year old younger vascular ageing indexes measured by carotid intimal media thickness, coronary artery calcium scores and leucocyte telomere length longer than those abstainers subjects at same age. The investigators hypothesized that regular wine consumers present less coronary lesion and coronary calcium score on coronary tomographic angiography, lower carotid intimal media thickness and higher mean telomere length due the benefice of wine.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Oct 2009
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2009
CompletedFirst Submitted
Initial submission to the registry
December 28, 2010
CompletedFirst Posted
Study publicly available on registry
December 29, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2011
CompletedDecember 29, 2010
September 1, 2010
1.4 years
December 28, 2010
December 28, 2010
Conditions
Keywords
Study Arms (1)
red wine
red wine usual consumer versus abstemious
Eligibility Criteria
male subjects, between 50 years-old and 70 years-old, divided in 2 groups: usual red wine consumers and red wine abstemious
You may qualify if:
- healthy male, from 50 years-old to 70 years-old.
You may not qualify if:
- asiatic or with manifest atherosclerosis disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Heart Insitute ( InCor) University of Sao Paulo
São Paulo, São Paulo, 05403-000, Brazil
Biospecimen
total blood sample
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Protasio L Da Luz, MD, PhD
University of Sao Paulo
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
December 28, 2010
First Posted
December 29, 2010
Study Start
October 1, 2009
Primary Completion
March 1, 2011
Study Completion
April 1, 2011
Last Updated
December 29, 2010
Record last verified: 2010-09