NCT01267552

Brief Summary

To study the safety of not draining the axilla, after breast conserving surgery and full axillary lymphadenectomy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
240

participants targeted

Target at P75+ for phase_2 breast-cancer

Timeline
Completed

Started Jul 2000

Longer than P75 for phase_2 breast-cancer

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2000

Completed
7.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2007

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2007

Completed
3.1 years until next milestone

First Submitted

Initial submission to the registry

December 27, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 28, 2010

Completed
Last Updated

December 28, 2010

Status Verified

July 1, 2010

Enrollment Period

7.2 years

First QC Date

December 27, 2010

Last Update Submit

December 27, 2010

Conditions

Keywords

Breast cancerSurgeryComplicationsDrainageSeroma

Outcome Measures

Primary Outcomes (1)

  • Safety

    The safety of not draining the axilla, will be considered by the total number of patients without complication among breast cancer patients treated by means of breast conserving surgery and full axillary lymphadenectomy

    6 months

Secondary Outcomes (1)

  • Serous fluid

    6 months

Study Arms (2)

Non drainage arm

EXPERIMENTAL

No drains will be placed during operation

Procedure: Non drains will be placed during operation

Drainage arm

ACTIVE COMPARATOR

Closed suction drains will be placed during operation

Procedure: Closed suction drainage

Interventions

Non drains will be placed during operation

Also known as: No drainage
Non drainage arm

Closed suction drainage will be placed during operation

Drainage arm

Eligibility Criteria

Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Stage I and II breast cancer patients
  • Will be submitted to breast conserving therapy, with full axillary lymphadenectomy

You may not qualify if:

  • diabetes

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Hospital Araujo Jorge, Associacao de Combate ao Cancer em Goias

Goiânia, Goiás, 74605070, Brazil

Location

Mastology Program of Federal University of Goias

Goiânia, Goiás, 74605070, Brazil

Location

Related Publications (1)

  • Freitas-Junior R, Ribeiro LFJ, Moreira MAR, Queiroz GS, Esperidiao MD, Silva MAC, Pereira RJ, Zampronha RAC, Rahal RMS, Soares LR, Dos Santos DL, Thomazini MV, de Faria CFS, Paulinelli RR. Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trial. Clinics (Sao Paulo). 2017 Jul;72(7):426-431. doi: 10.6061/clinics/2017(07)07.

MeSH Terms

Conditions

Breast NeoplasmsSeroma

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue DiseasesInflammationPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Ruffo Freitas-Junior, PhD

    Universidade Federal de Goias

    PRINCIPAL INVESTIGATOR
  • Luiz Fernando J Ribeiro, PhD

    Hospital Araujo Jorge, Associacao de Combate ao Cancer em Goias

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

December 27, 2010

First Posted

December 28, 2010

Study Start

July 1, 2000

Primary Completion

September 1, 2007

Study Completion

December 1, 2007

Last Updated

December 28, 2010

Record last verified: 2010-07

Locations