Evaluation of the Proliferative Activities of Insulin Analogues in Primary Human Tumor Cells
1 other identifier
expanded_access
N/A
0 countries
N/A
Brief Summary
Recently the general medical literature has become aware that the use of certain long-acting insulin analogues could potentially increase cancer risk.During the last few years the investigators group generated information of both scientific and clinical relevance on the proliferative and anti-apoptotic actions of insulin analogues. The goal of this project is to evaluate the hypothesis that the proliferative and signalling activities elicited by insulin analogues may have a impact on tumor behavior. In this study the investigators will asses the biological actions of insulin analogs in primary tumor cells of endometrial and colon cancer.
Trial Health
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 27, 2010
CompletedFirst Posted
Study publicly available on registry
December 28, 2010
CompletedAugust 10, 2012
August 1, 2012
December 27, 2010
August 9, 2012
Conditions
Keywords
Interventions
Endometrial cancer specimens will be obtained from patients operated and treated at the Gynecologic Oncology Unit at Meir Medical Center. Colon cancer specimens will be obtained from patients that underwent colonoscopy at the Gastrointestinal Department at Meir Medical Center.
Eligibility Criteria
You may qualify if:
- Patients with Endometrial and Colon Cancer
You may not qualify if:
- None
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Meir Medical Centerlead
- Tel Aviv Universitycollaborator
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- expanded access
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 27, 2010
First Posted
December 28, 2010
Last Updated
August 10, 2012
Record last verified: 2012-08