NCT01265290

Brief Summary

The purpose of this study is to assess efficacy of prolonged Full Disclosure electrocardiogram (ECG) monitoring and signal analysis using advanced telemetric technology to diagnose syncope in comparison with standard diagnostic procedure

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
640

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2011

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 22, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 23, 2010

Completed
1 month until next milestone

Study Start

First participant enrolled

February 1, 2011

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2012

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2013

Completed
Last Updated

December 5, 2011

Status Verified

December 1, 2011

Enrollment Period

1.8 years

First QC Date

December 22, 2010

Last Update Submit

December 2, 2011

Conditions

Keywords

Cardiac arrhythmiaCardiogenic syncopePediatricsChildren

Outcome Measures

Primary Outcomes (1)

  • Recording of symptomatic or life threatening arrhythmia event

    ECG monitoring is conducted until occurrence of symptomatic arrhythmia or life threatening arrhythmia but not longer than 30 days. Patients in the control group will have standard ECG Holter monitoring repeated twice

    within 30 days since the start of monitoring

Secondary Outcomes (2)

  • Occurrence of silent (asymptomatic) arrhythmia event

    within 30 days since the start of monitoring

  • 1. Verification of patient self assessment based on the Quality of Life questionnaire and EHRA scale against evidence of cardiac arrhythmia occurrence

    within 30 days since the start of monitoring

Study Arms (2)

Telemetric ECG monitoring

EXPERIMENTAL

Telemetric Full Disclosure ECG monitoring

Device: Telemetric ECG monitoring

24 hours standard Holter monitoring

EXPERIMENTAL
Device: repeated 24 hours ECG Holter monitoring

Interventions

repeated 24 hours ECG Holter monitoring

24 hours standard Holter monitoring

Telemetric ECG full disclosure monitoring with GSM technology

Telemetric ECG monitoring

Eligibility Criteria

AgeUp to 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • History of syncope
  • Ability to operate the telemetric device at home
  • informed consent undersigned by the parents
  • informed consent undersigned by the child if over 16 years of age

You may not qualify if:

  • Syncope with known underlying disease
  • Inability to operate the telemetric device at home
  • Complete Heart block
  • QT\>500ms
  • Implantation of ICD
  • Inability to comply with the study protocol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Medical University of Warsaw Department of Pediatric Cardiology and General Pediatrics

Warsaw, 00-576, Poland

RECRUITING

The Children's Memmorial Health Institute

Warsaw, 04-730, Poland

RECRUITING

MeSH Terms

Conditions

Arrhythmias, CardiacSyncope

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and SymptomsUnconsciousnessConsciousness DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and Symptoms

Study Officials

  • Lukasz Szumowski, Prof. MD PhD

    National Institute of Cardiology, Warsaw, Poland

    STUDY CHAIR
  • Katarzyna Bieganowska, Prof. MD PhD

    Children's Memorial Health Institute

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Katarzyna Bieganowska, Prof. MD PhD

CONTACT

Maria Miszczak-Knecht, MD, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

December 22, 2010

First Posted

December 23, 2010

Study Start

February 1, 2011

Primary Completion

December 1, 2012

Study Completion

January 1, 2013

Last Updated

December 5, 2011

Record last verified: 2011-12

Locations