NCT01260441

Brief Summary

Each year in the United States, 300,000 people suffer from a Cardiac Arrest (CA), and of them, there is a 90% mortality rate. Out-of-Hospital arrests, in particular, have a 1-5% survival to hospital discharge. High quality CPR is crucial to lowering the mortality rate and increasing survival, yet only 15-30% of out-of-hospital CA victims receive bystander CPR. Studies have shown that prompt administration of CPR dramatically improves outcomes. In a recent study from Switzerland, lay bystander CPR doubled the survival rate at one month. Our study will look to train family members of at-risk cardiac patients in the skills of CPR through the American Heart Association's (AHA) CPR Anytime Friends and Family Personal Learning Program (CPR Anytime) to see if these family members are able to learn and perform quality CPR in the event that their family member should suffer a cardiac arrest.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Oct 2007

Longer than P75 for phase_1

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2007

Completed
3.2 years until next milestone

First Submitted

Initial submission to the registry

November 29, 2010

Completed
16 days until next milestone

First Posted

Study publicly available on registry

December 15, 2010

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2012

Completed
Last Updated

November 1, 2018

Status Verified

October 1, 2018

Enrollment Period

5 years

First QC Date

November 29, 2010

Last Update Submit

October 31, 2018

Conditions

Cardiac ArrestCoronary DiseaseCardiovascular Risk Factors

Outcome Measures

Primary Outcomes (2)

  • Subject Self-Confidence

    We will administer a comprehensive post-training likert scale scoring survey to measure the subject's comfort level using their newly acquired CPR skills.

    within 30 minutes of CPR training

  • Secondary Training

    In addition, we will administer a telephone survey to measure the subject's secondary training through the CPR Anytime Kit.

    3 month increments over a 12 month period of time

Secondary Outcomes (1)

  • Assessing CPR Skills

    3 to 6 months post-training

Study Arms (2)

Standard CPR

ACTIVE COMPARATOR

Individuals will learn the Standard form of CPR (30:2, compressions:breathes) Main data points being collected over various increments are: 1) Comfort Level with using CPR 2) Secondary Training "multiplier effect" and 3) CPR Skills

Other: CPR Training using the Family and Friends CPR Anytime VSI Kit

Chest Compressions Only CPR

ACTIVE COMPARATOR

Individuals will learn the chest compression only form of CPR (no rescue breathes) Main data points being collected at various increments are: 1) Comfort Level with using CPR 2) Secondary Training "multiplier effect" and 3) CPR Skills

Other: CPR Training using the Family and Friends CPR Anytime VSI Kit

Interventions

CPR Training using the Family and Friends CPR Anytime VSI KitOTHER

Subjects will be trained using the American Heart Association's Family and Friends CPR Anytime Kit. Subjects will undergo training in-hospital and will be encouraged to take the kit home to share with their family members and friends.

Also known as: Family and Friends CPR Anytime, American Heart Association Family and Friends CPR Anytime, CPR Anytime Video Self Instruction (VSI)
Chest Compressions Only CPRStandard CPR

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Family member's of patients with known coronary disease or cardiovascular risk factors, such as history of diabetes and hypertension.

You may not qualify if:

  • If someone is physically unable to undergo CPR Training
  • Someone who has received CPR training in the past 2 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Location

Penn Presbyterian Medical Center

Philadelphia, Pennsylvania, 19104, United States

Location

Pennsylvania Hospital

Philadelphia, Pennsylvania, 19106, United States

Location

Related Publications (1)

  • Blewer AL, Leary M, Esposito EC, Gonzalez M, Riegel B, Bobrow BJ, Abella BS. Continuous chest compression cardiopulmonary resuscitation training promotes rescuer self-confidence and increased secondary training: a hospital-based randomized controlled trial*. Crit Care Med. 2012 Mar;40(3):787-92. doi: 10.1097/CCM.0b013e318236f2ca.

    PMID: 22080629DERIVED

MeSH Terms

Conditions

Heart ArrestCoronary Disease

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesMyocardial IschemiaVascular Diseases

Study Officials

  • Benjamin S Abella, MD, MPhil

    University of Pennsylvania

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 29, 2010

First Posted

December 15, 2010

Study Start

October 1, 2007

Primary Completion

October 1, 2012

Study Completion

October 1, 2012

Last Updated

November 1, 2018

Record last verified: 2018-10

Locations

US(3)