NCT01260311

Brief Summary

This is an observational study and will determine the safety profile of fesoterodine in Filipino patients prescribed the drug. This is in compliance with the requirements of the Philippine Food and Drug Administration.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
508

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2011

Typical duration for all trials

Geographic Reach
1 country

37 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 22, 2010

Completed
23 days until next milestone

First Posted

Study publicly available on registry

December 15, 2010

Completed
2 months until next milestone

Study Start

First participant enrolled

February 1, 2011

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2013

Completed
12 months until next milestone

Results Posted

Study results publicly available

September 11, 2014

Completed
Last Updated

September 11, 2014

Status Verified

September 1, 2014

Enrollment Period

2.7 years

First QC Date

November 22, 2010

Results QC Date

September 4, 2014

Last Update Submit

September 4, 2014

Conditions

Keywords

Observational

Outcome Measures

Primary Outcomes (1)

  • Number of Participants With Adverse Events (AEs) by Seriousness, Severity and Relationship to Treatment

    Counts of participants who had treatment-emergent AEs (TEAEs), defined as newly occurring or worsening after first dose. Relatedness to fesoterodine fumarate (Toviaz) was assessed by the investigator. Participants with multiple occurrences of an AE within a category were counted once within the category. Seriousness of an AE was assessed under the criteria of serious adverse event (SAE). AE was assessed according to severity; mild (not causing any significant problem, dose adjustment not required), moderate (caused problem that does not interfere significantly with usual activities or the clinical status, dose adjustment needed due to AE) and severe (caused problem that interferes significantly with usual activities or the clinical status, study drug stopped due to AE).

    Baseline up to 28 days after last dose

Other Outcomes (4)

  • Number of Micturitions Per 24 Hours at Week 4 and Week 8

    Week 4 and Week 8

  • Number of Urgency Episodes Per 24 Hours at Week 4 and Week 8

    Week 4 and Week 8

  • Number of UUI Episodes Per 24 Hours at Week 4 and Week 8

    Week 4 and Week 8

  • +1 more other outcomes

Study Arms (1)

Patients prescribed with Fesoterodine

Patients diagnosed with Over-active bladder and prescribed with fesoterodine.

Drug: Fesoterodine

Interventions

Any dose of Fesoterodine

Also known as: Toviaz
Patients prescribed with Fesoterodine

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients diagnosed with Over-active bladder

You may qualify if:

  • Over-active bladder
  • Prescribed with Fesoterodine

You may not qualify if:

  • Hypersensitivity
  • Urinary retention

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (37)

Mary Johnston Hospital, Inc.

Tondo, Manila, 1000, Philippines

Location

East Avenue Medical Center

Diliman, Quezon City, National Capital Region, 1101, Philippines

Location

The Medical City

Pasig, National Capital Region, 1605, Philippines

Location

St. Luke's Medical Center

Quezon City, National Capital Region, 1102, Philippines

Location

Private Clinic

Baguio City, Philippines

Location

Private Clinic

Batangas, Philippines

Location

Cebu Doctors Hospital, Osmena Blvd.,

Cebu, Philippines

Location

Private Clinic

City of Muntinlupa, Philippines

Location

Davao Doctors Hospital

Davao City, Philippines

Location

Davao Doctors Tower

Davao City, Philippines

Location

Davao Medical School Foundation Hospital

Davao City, Philippines

Location

Private Clinic

Davao City, Philippines

Location

Room 120, Davao Medical School Foundation Hospital

Davao City, Philippines

Location

Private Clinic

Ilocos Norte, Philippines

Location

Private Clinic

La Union, Philippines

Location

Private Clinic

Laguna, Philippines

Location

Lucena United Doctors Hospital

Lucena City, 4301, Philippines

Location

Makati Medical Center

Makati City, 1200, Philippines

Location

Private Clinic

Makati City, Philippines

Location

Room 314 Main Building

Makati City, Philippines

Location

VRPMC

Mandaluyong, Philippines

Location

Medical Center Manila

Manila, 1000, Philippines

Location

University of Sto. Tomas Hospital

Manila, 1000, Philippines

Location

Ospital ng Maynila Medical Center

Manila, Philippines

Location

Private Clinic

Manila, Philippines

Location

Santo Tomas University Hospital

Manila, Philippines

Location

Private Clinic

Nueva Ecija, Philippines

Location

Healthway Medical, The Block

Philippines, Philippines

Location

East Avenue Medical Center

Quezon, Philippines

Location

Private Clinic

Quezon, Philippines

Location

St. Luke's Medical Center, North Tower, CHBC

Quezon City, 1100, Philippines

Location

Private Clinic

Quezon City, Philippines

Location

Private Clinic

South Luzon, Philippines

Location

Central Luzon Doctor's Hospital

Tarlac City, Philippines

Location

Fatima Medical Center, Inc.

Valenzuela, Philippines

Location

F.E.U. - Nicanor Reyes Medical Foundation Medical Center

West Fairview, Quezon City, 1100, Philippines

Location

Urology Clinic

Zamboanga City, Philippines

Location

Related Links

MeSH Terms

Interventions

fesoterodine

Limitations and Caveats

The implementation of Protocol Amendment 1 led to removal of all primary efficacy outcome measures, therefore the efficacy outcome measures were not investigated or reported.

Results Point of Contact

Title
Pfizer ClinicalTrials.gov Call Center
Organization
Pfizer, Inc.

Study Officials

  • Pfizer CT.gov Call Center

    Pfizer

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 22, 2010

First Posted

December 15, 2010

Study Start

February 1, 2011

Primary Completion

October 1, 2013

Study Completion

October 1, 2013

Last Updated

September 11, 2014

Results First Posted

September 11, 2014

Record last verified: 2014-09

Locations