Allogene MSCs Transplantation in Patients With Chronic Liver Diseases Through Peripheral Vein.

NCT01256125 | Unknown DMC

• 1 other identifier: SunYat-sen U 11-5-1
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Allogene MSCs transplantation will be performed in patients with chronic liver diseases through peripheral vein and therapeutic effects including short-term effects and long-term follow-up will be compared and investigated.

Conditions

Allogene MSCs Transplantation; Chronic Liver Diseases Patients; Peripheral Vein

Keywords

allogene MSCs; transplantation; chronic liver diseases; peripheral vein

Outcome Measures

Primary Outcomes (1)

• Short-term therapeutic effects at 1-8 weeks after Allogene MSCs transplantation through peripheral vein.

  1-8 weeks after transplantation

Secondary Outcomes (1)

• Long-term follow-up of Allogene MSCs transplantation through peripheral vein.

  3-60 months

Study Arms (2)

Allogene MSCs transplantation

Allogene MSCs transplantation were performed in patients with chronic liver diseases through peripheral vein plus the same medical treatments.

control

only medical treatments were performed in patients with chronic liver diseases.

Eligibility Criteria

• Age: 15 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with chronic liver diseases including: viral hepatitis, alcoholic liver disease, autoimmune liver disease and so on.

You may qualify if:

• chronic liver diseases including: viral hepatitis, alcoholic liver disease, autoimmune liver disease.
• age: 15-65 years old.

You may not qualify if:

• pregnant women and women in lactation.
• other systems and organs disfunction
• space-occupying lesion were found in liver.
• concurrent infection with HIV and other immunodeficiency diseases.
• DIC and active bleeding were confirmed.

Sponsors & Collaborators

• Sun Yat-sen University: lead

Study Sites (1)

Department of Infectious Diseases, 3rd Affiliated Hospital of Sun Yat-sen University

Guangzhou, Guangdong, 510630, China

RECRUITING

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: December 7, 2010
• First Posted: December 8, 2010
• Study Start: October 1, 2010
• Last Updated: December 8, 2010

Record last verified: 2010-10

Locations

CN (1)