The Sinonasal Outcome Test - 22, Validated for Danish Patients

NCT01254916 | Completed

• 1 other identifier: Danish SNOT 22
• Study Type: observational
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

Introduction: Chronic rhinosinusitis (CRS) is a significant health problem increasing in both incidence and prevalence. It calls into attention consensus about diagnosing, assessing symptoms and treatment of patients with CRS. Therefore a validated Danish measure of health-related quality of life in sinonasal disease is needed. Method: The Sinonasal Outcome measure 22 (SNOT-22) was translated into Danish and reproducibility was evaluated by test-retesting 40 patients with CRS. The statistical analyses used, were Pearson´s correlation coefficient, Cronbach´s alfa, Kappa and Bland-Altman´s Plot. Reproducibility was also tested looking at subscales within the SNOT-22. Result: The results show good internal correlation with Cronbach´s alfa at 0.83 in the initial test and 0.92 in the retest. Pearson was 0.70 (p\<0.001) revealing good correlation between the initial scores and the retests scores. Kappa was calculated for each item with a mean value of 0.61 showing substantial agreement. Paired t-test revealed no significant difference in the subscales. Conclusion: The Danish version of SNOT-22 is recommended for Danish clinicians and researches as a patient-reported measure of outcome in sino-nasal disorders such as rhinosinusitis and nasal polyposis.

Conditions

Chronic Rhinosinusitis

Keywords

Chronic Rhinosinusitis; Sinonasal Outcome test 22

Outcome Measures

Primary Outcomes (1)

• Reproducibility of Sinonasal Outcome test 22

  From the time of fullfilling the first SNOT-22 to fullfilling the second SNOT-22 after 14 days

Study Arms (1)

Patients with chronic rhinosinusitis

Eligibility Criteria

• Age: 15 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with chronic rhinosinusitis diagnosed by a medical doctor

Sponsors & Collaborators

• Odense University Hospital: lead

Study Sites (1)

Department of Otorhinolaryngology, Odense University Hopsital

Odense, DK-5000, Denmark

Location

Related Publications (1)

• Lange B, Thilsing T, Al-kalemji A, Baelum J, Martinussen T, Kjeldsen A. The Sino-Nasal Outcome Test 22 validated for Danish patients. Dan Med Bull. 2011 Feb;58(2):A4235.

  PMID: 21299922 DERIVED

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD, Ph.d.-student

Study Record Dates

• First Submitted: December 6, 2010
• First Posted: December 7, 2010
• Study Start: October 1, 2008
• Primary Completion: March 1, 2009
• Study Completion: March 1, 2009
• Last Updated: May 8, 2012

Record last verified: 2012-05

Locations

DK (1)