NCT01247181

Brief Summary

The investigators hypothesize that sending weekly motivational text messages to people infected with HIV will encourage them to take their medication, compared to usual care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2010

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2010

Completed
21 days until next milestone

First Submitted

Initial submission to the registry

November 22, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 24, 2010

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2011

Completed
Last Updated

September 8, 2011

Status Verified

September 1, 2011

Enrollment Period

8 months

First QC Date

November 22, 2010

Last Update Submit

September 7, 2011

Conditions

AdherenceHIV

Keywords

complianceobservancemobile phoneSMStext messageARVHAARTAIDS

Outcome Measures

Primary Outcomes (1)

  • Adherence

    Measured using the Visual Analogue Scale, Self Report and Pharmacy Refill Data

    Change from baseline at 6 months

Secondary Outcomes (8)

  • Weight

    Change from baseline at 6 months

  • Body Mass Index

    Change from baseline at 6 months

  • CDC classification

    Change from baseline at 6 months

  • WHO Classification

    Change from baseline at 6 months

  • Mortality

    6 months

  • +3 more secondary outcomes

Study Arms (2)

Mobile phone text message

EXPERIMENTAL
Other: Mobile phone text message

No Mobile phone text message

ACTIVE COMPARATOR

Usual care provided at clinic

Other: Usual care

Interventions

Mobile phone text messageOTHER

Weekly message with motivational content

Also known as: SMS, Texto, Text message
Mobile phone text message
Usual careOTHER

Usual care provided at clinic

Also known as: Routine care
No Mobile phone text message

Eligibility Criteria

Age21 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • On HAART for at least 1 month
  • years or more
  • Owns a mobile phone
  • Can read text messages

You may not qualify if:

  • On HAART for less than 1 month
  • Aged less than 21 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yaounde Central Hospital Accredited Treatment Centre

Yaoundé, Centre Region, Cameroon

Location

Related Publications (2)

  • Mbuagbaw L, Thabane L, Ongolo-Zogo P, Lester RT, Mills EJ, Smieja M, Dolovich L, Kouanfack C. The Cameroon Mobile Phone SMS (CAMPS) trial: a randomized trial of text messaging versus usual care for adherence to antiretroviral therapy. PLoS One. 2012;7(12):e46909. doi: 10.1371/journal.pone.0046909. Epub 2012 Dec 6.

    PMID: 23236345DERIVED

  • Mbuagbaw L, Thabane L, Ongolo-Zogo P, Lester RT, Mills E, Volmink J, Yondo D, Essi MJ, Bonono-Momnougui RC, Mba R, Ndongo JS, Nkoa FC, Ondoa HA. The Cameroon mobile phone SMS (CAMPS) trial: a protocol for a randomized controlled trial of mobile phone text messaging versus usual care for improving adherence to highly active anti-retroviral therapy. Trials. 2011 Jan 7;12:5. doi: 10.1186/1745-6215-12-5.

    PMID: 21211064DERIVED

MeSH Terms

Conditions

Patient ComplianceAcquired Immunodeficiency Syndrome

Condition Hierarchy (Ancestors)

Patient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehaviorHIV InfectionsBlood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesSlow Virus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System Diseases

Study Officials

  • Lawrence Mbuagbaw, MD, MPH

    Centre for the Development of Best Practices in Health

    PRINCIPAL INVESTIGATOR

  • Pierre Ongolo-Zogo, MD, BSc

    Centre for the Development of Best Practices in Health

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, MPH

Study Record Dates

First Submitted

November 22, 2010

First Posted

November 24, 2010

Study Start

November 1, 2010

Primary Completion

July 1, 2011

Study Completion

July 1, 2011

Last Updated

September 8, 2011

Record last verified: 2011-09

Locations

CA(1)