NCT01242696

Brief Summary

The goal of the TAXUS™ Element™ Paclitaxel-Eluting Coronary Stent System European Post-Approval Surveillance Study is to evaluate real world clinical outcomes data for the TAXUS™ Element™ Coronary Stent System in unselected patients in routine clinical practice.

Trial Health

98
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,014

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2010

Longer than P75 for all trials

Geographic Reach
10 countries

37 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2010

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

November 16, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 17, 2010

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2013

Completed
2.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2015

Completed
Last Updated

February 3, 2017

Status Verified

February 1, 2017

Enrollment Period

2.3 years

First QC Date

November 16, 2010

Last Update Submit

February 2, 2017

Conditions

Keywords

Drug Eluting StentsObservationalAll-Comers

Outcome Measures

Primary Outcomes (1)

  • Target Vessel failure

    Overall and TAXUS Element stent related Target Vessel Failure (TVF) rate (cardiac death, myocardial infarction (MI) related to target vessel and target vessel re-intervention (TVR)) at 12 months post stent implantation

    1 year

Secondary Outcomes (9)

  • Stent Thrombosis

    30 days, 6 months, 12 months and then annually through 3 years post index stent implantation

  • MACE

    30 days, 6 months, 12 months and then annually through 3 years post index stent implantation

  • Cardiac Death or MI

    30 days, 6 months, 12 months and then annually through 3 years post index stent implantation

  • TVR

    30 days, 6 months, 12 months and then annually through 3 years post index stent implantation

  • Cardiac Death

    30 days, 6 months, 12 months and then annually through 3 years post index stent implantation

  • +4 more secondary outcomes

Study Arms (1)

Coronary artery stenting

All subjects who are candidates for coronary artery stenting, signed the Informed Consent Form and are eligible to receive a TAXUS Element stent will be evaluated for enrollment in this study.

Procedure: Coronary artery stenting

Interventions

Coronary artery stenting with drug eluting stents

Also known as: TAXUS Element
Coronary artery stenting

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All subjects who are candidates for coronary artery stenting, signed the Informed Consent Form and are eligible to receive a TAXUS Element stent will be evaluated for enrollment in this study.

You may qualify if:

  • According to Instructions For Use

You may not qualify if:

  • Contraindications according to Instructions for Use

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (37)

Algemeen Ziekenhuis Sint-Jan

Bruges, 8000, Belgium

Location

CHU de Charleroi - ISPPC

Charleroi, 6000, Belgium

Location

H-Hartziekenhuis Roeselare-Menen vzw

Roeselare, 8800, Belgium

Location

CH Avignon

Avignon, 84902, France

Location

CHU Besancon

Besançon, 25030, France

Location

Centre Hospitalier Privé Saint Martin gds

Caen, 14000, France

Location

CHU Grenoble

Grenoble, 38043, France

Location

Hôpital Privé Clairval

Marseille, 13006, France

Location

CHG de Pau

Pau, 64046, France

Location

Clinique Saint-Hilaire Rouen

Rouen, 7600, France

Location

Centre Hôpital Universitaire Rangueuil

Toulouse, 31059, France

Location

Kardiocentrum Frankfurt

Frankfurt am Main, Hesse, 60316, Germany

Location

Krankenhaus d. Barmherzigen Brüder

Trier, Rhineland-Palatinate, 76133, Germany

Location

Klinikum Coburg gGmbH

Coburg, 96450, Germany

Location

Zentrum für klinische Prüfungen in der Facharztzentrum Dresden-Neustadt GbR

Dresden, 1324, Germany

Location

Augusta Krankenhaus

Düsseldorf, 40472, Germany

Location

Krankenhaus Landshut-Achdorf

Landshut, 84036, Germany

Location

Medical School of University PECS

Pécs, 7632, Hungary

Location

Galway University Hospital

Galway, Ireland

Location

Ospedale Ferrarotto

Catania, 95100, Italy

Location

Ospedale Cannizzaro

Catania, 95126, Italy

Location

Ospedale Misericordia ASL 9

Grosseto, 58100, Italy

Location

Azienda Ospedaliera Papardo

Messina, 98161, Italy

Location

P. Stradins University Hospital

Riga, LV-1002, Latvia

Location

Samodzielny Publiczny Specjalistyczny Szpital Zachodni im. Jana Pawla II

Grodzisk Mazowiecki, 05-825, Poland

Location

Hospital General de Albacete

Albacete, 2006, Spain

Location

Hospital Universitario de Bellvitge

Barcelona, 8907, Spain

Location

Hospital General De Leon

León, 24008, Spain

Location

Hospital La Paz

Madrid, 28046, Spain

Location

H. Marques De Valdecilla

Santander, 39008, Spain

Location

Craigavon Hospital, Southern Trust

Craigavon, Northern Ireland, BT63 5QQ, United Kingdom

Location

Royal Bournemouth General Hospital

Bournemouth, BH7 7DW, United Kingdom

Location

Lister

Hertfordshire, United Kingdom

Location

London Chest Hospital

London, E2 9JX, United Kingdom

Location

Freeman Hospital

Newcastle upon Tyne, NE7 7DN, United Kingdom

Location

Norfolk and Norwich University Hospital NHS Trust

Norwich, NR4 &UY, United Kingdom

Location

New Cross Hospital

Wolverhampton, WV10 0QP, United Kingdom

Location

Related Publications (1)

  • Tamburino C, Capodanno D, Erglis A, Menown IB, Horvath IG, Moreno R, Gilbert TJ, Crowley JJ, Calabria P, Allocco DJ, Dawkins KD. One-year outcomes in unselected patients treated with a thin-strut, platinum-chromium, paclitaxel-eluting stent: primary endpoint results from the TAXUS Element European post-approval surveillance study (TE-PROVE). EuroIntervention. 2015 Mar;10(11):1261-6. doi: 10.4244/EIJY15M01_01.

MeSH Terms

Conditions

Coronary Disease

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular Diseases

Study Officials

  • Corrado Tamburino, Prof.

    Ospedale Ferrarotto, Via Citelli, 1, 95100 Catania, Italy

    PRINCIPAL INVESTIGATOR
  • Peter Maurer, PhD

    Boston Scientific Corporation

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 16, 2010

First Posted

November 17, 2010

Study Start

November 1, 2010

Primary Completion

March 1, 2013

Study Completion

July 1, 2015

Last Updated

February 3, 2017

Record last verified: 2017-02

Data Sharing

IPD Sharing
Will not share

Primary endpoint data presented at TCT 2014.

Locations