Vercise Implantable Stimulator for Treating Parkinson's Disease

You may not qualify if:

• Any intracranial abnormality or medical condition that would contraindicate DBS surgery.
• Any finding in neuropsychological screening assessments that would contraindicate DBS surgery, including dementia.
• Any significant psychiatric problems, including unrelated clinically significant depression.
• Any current drug or alcohol abuse.
• Any history of recurrent or unprovoked seizures.
• Frequent falls while receiving good medication therapy without dyskinesias (on-state).
• Any prior movement disorder treatments that involved intracranial surgery or device implantation.
• Any other active implanted device.
• Any previous brain surgery that would interfere with the placement of the leads or the functioning of the device.
• A history of neurostimulation intolerance in any area of the body.
• A condition requiring or likely to require the use of magnetic resonance imaging (MRI) or diathermy.
• Currently on any anticoagulant medications that can not be discontinued during perioperative period.
• Have any significant medical condition that is likely to interfere with study procedures or likely to confound evaluation of study endpoints, including any terminal illness with survival \<12 months.
• Participation in another drug, device, or biologics trial concurrently or within the preceding 30 days. Any other trial participation should be approved by the Principal Investigators.
• A female that is breastfeeding or of child bearing potential with a positive urine pregnancy test or not using adequate contraception.