NCT01219946

Brief Summary

Chronic obstructive pulmonary disease (COPD) is characterized by a progressive decline in lung function and increased symptoms such as breathlessness/dyspnoea, cough and expectoration. Even though subjective in nature, the symptomatology of COPD and mainly that of breathlessness/dyspnoea has been studied with the use of objective measurement tools. Taking into consideration that the symptoms experienced by the patient who suffers from a progressive disease such as COPD can only be perceived and interpreted by the patient him- or herself, and thus difficult to be quantified, COPD remains a challenge in clinical research. Therefore, there is a need to carry out qualitative studies that will provide insight into the wide spectrum of COPD symptomatology from the patient's perspective. In addition, a further mapping of the impact that COPD symptoms' perception has on a patient's life is required, as well as of the different pathways through which symptoms' perception is interpreted regarding the limitations of daily living activities, and the subsequent impact on disease management. The more the physician learns on the embodied experience of COPD, the better he/she may assist the patient in achieving optimal COPD management. Thus this cross-sectional observational study was designed aiming to obtain these data. Specifically, the study aims to evaluate the most frequently used words by the patients and the physicians to express the symptoms of COPD as well as the limitation of activities that it causes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
700

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2010

Shorter than P25 for all trials

Geographic Reach
1 country

32 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2010

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

October 8, 2010

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 13, 2010

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2011

Completed
Last Updated

March 21, 2012

Status Verified

March 1, 2012

Enrollment Period

5 months

First QC Date

October 8, 2010

Last Update Submit

March 20, 2012

Conditions

Keywords

Chronic Obstructive Pulmonary Disease, symptoms

Outcome Measures

Primary Outcomes (1)

  • Words used by the patients and the physicians to express the symptoms of COPD as well as the limitations of patients' daily living activities caused by COPD.

    End of recruitment (estimated timeframe :2.5 months)

Secondary Outcomes (20)

  • Age

    End of recruitment (estimated timeframe :2.5 months)

  • Gender

    End of recruitment (estimated timeframe :2.5 months)

  • Place of residence

    End of recruitment (estimated timeframe :2.5 months)

  • Marital status

    End of recruitment (estimated timeframe :2.5 months)

  • Native language

    End of recruitment (estimated timeframe :2.5 months)

  • +15 more secondary outcomes

Study Arms (1)

1

Patients with Chronic Obstructive Pulmonary Disease

Eligibility Criteria

Age45 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with Chronic Obstructive Pulmonary Disease

You may qualify if:

  • Aged 45-75 years
  • Current or former smokers
  • Known history of COPD for at least 6 months before enrolment into the study documented by spirometry (FEV1 /FVC \<70%)
  • Patients with stable COPD (no exacerbation within the last month before enrolment into the study) under treatment with a long-acting inhaled bronchodilator (LABA and/or LAMA) alone or in combination with an inhaled corticosteroid
  • Written consent for participation in the study
  • Patients who are able to complete by themselves in Greek a questionnaire on COPD.

You may not qualify if:

  • Patients with diagnosed Asthma
  • Patients with any psychiatric, neurological or other disorder render them unable to complete the COPD questionnaire by themselves
  • The patient participates in another study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (32)

Research Site

Athens, Attica, Greece

Location

Research Site

Kallithea, Attica, Greece

Location

Research Site

Marousi, Attica, Greece

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Research Site

Megara, Attica, Greece

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Research Site

Nea Ionia, Attica, Greece

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Research Site

Nea Makri, Attica, Greece

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Research Site

Piraeus, Attica, Greece

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Research Site

Chania, Crete, Greece

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Research Site

Heraklion, Crete, Greece

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Rhodes, Dodekanisa, Greece

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Corfu, Eptanisa, Greece

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Research Site

Ioannina, Ipiros, Greece

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Larissa, Kyklades, Greece

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Research Site

Mykonos, Kyklades, Greece

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Research Site

Alexándreia, Makedonia, Greece

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Research Site

Drama, Makedonia, Greece

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Florina, Makedonia, Greece

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Research Site

Katerini, Makedonia, Greece

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Research Site

Kavala, Makedonia, Greece

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Kozani, Makedonia, Greece

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Research Site

Serres, Makedonia, Greece

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Research Site

Thesaloniki, Makedonia, Greece

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Research Site

Krestena, Peloponisos, Greece

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Research Site

Lechainá, Peloponisos, Greece

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Research Site

Pátrai, Peloponisos, Greece

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Research Site

Skála, Peloponisos, Greece

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Research Site

Agrinio, Sterea, Greece

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Research Site

Halkida, Sterea, Greece

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Research Site

Itea, Sterea, Greece

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Research Site

Livadia, Sterea, Greece

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Research Site

Volos, Thesalia, Greece

Location

Research Site

Xánthi, Traki, Greece

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Panagiotis Pontikis

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 8, 2010

First Posted

October 13, 2010

Study Start

October 1, 2010

Primary Completion

March 1, 2011

Study Completion

March 1, 2011

Last Updated

March 21, 2012

Record last verified: 2012-03

Locations