The Effect of Aerobic Interval Training on Obstructive Sleep Apnea
2 other identifiers
interventional
30
1 country
1
Brief Summary
The purpose of this study is to investigate if 3 months of interval training improves obstructive sleep apnea in obese patients diagnosed with moderate to severe obstructive sleep apnea. The working hypothesis is that 3 months of 3 weekly aerobic interval training sessions improve obstructive sleep apnea and sleep quality in obese patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Oct 2010
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2010
CompletedFirst Submitted
Initial submission to the registry
October 4, 2010
CompletedFirst Posted
Study publicly available on registry
October 6, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2013
CompletedMarch 29, 2017
March 1, 2017
2.5 years
October 4, 2010
March 28, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Apnea-hypopnea index change
Measured by Polysomnography
Baseline, 3 and 6 months
Secondary Outcomes (1)
Sleep quality
Baseline, 3 and 6 months
Study Arms (2)
Aerobic Interval Training
EXPERIMENTALPatients randomized to training will meet for supervised aerobic interval training three times per week for 3 months. The interval training session consists of 10 minutes warm up and continues with 4 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate
Control
OTHERPatients will receive standard medical treatment at the University Hospital lung department.
Interventions
Treadmill walking or running - 3 times per week for 3 months. The interval training session consists of 10 minutes warm up and continues with 4 x 4 minutes high intensity intervals at 90-95% of maximal heart rate. Training intensity will be supervised through the use of Polar pulse monitors and the BORG scale of subjective perceived exhaustion.
Eligibility Criteria
You may qualify if:
- BMI ≥ 30 kg/M2
- Apne - hypopnea index (AHI) \> 10
- No significant comorbidities
- Abel to exercise
You may not qualify if:
- Inability to exercise due to musculoskeletal conditions
- Known ischemic cardiovascular disease
- Drug abuse
- Mental illnesses
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Norwegian University of Science and Technology
Trondheim, 7491, Norway
Related Publications (1)
Karlsen T, Nes BM, Tjonna AE, Engstrom M, Stoylen A, Steinshamn S. High-intensity interval training improves obstructive sleep apnoea. BMJ Open Sport Exerc Med. 2017 Feb 8;2(1):bmjsem-2016-000155. doi: 10.1136/bmjsem-2016-000155. eCollection 2016.
PMID: 29616142RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Trine Karlsen, PhD
Norwegian University of Science and Technology
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- INVESTIGATOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 4, 2010
First Posted
October 6, 2010
Study Start
October 1, 2010
Primary Completion
April 1, 2013
Study Completion
October 1, 2013
Last Updated
March 29, 2017
Record last verified: 2017-03
Data Sharing
- IPD Sharing
- Will not share