Exercise-induced Bronchoconstriction Diagnostics: Impact of a Repeated Exercise Challenge Test
1 other identifier
observational
20
1 country
1
Brief Summary
The purpose of this study is to increase the knowledge of the possible diagnostic effect of exercise induced bronchoconstriction performing a repeated exercise challenge test.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Aug 2010
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2010
CompletedFirst Submitted
Initial submission to the registry
September 23, 2010
CompletedFirst Posted
Study publicly available on registry
October 5, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2011
CompletedFebruary 9, 2017
February 1, 2017
7 months
September 23, 2010
February 7, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
Forced expiratory volume in one second (FEV1)
up to 4 weeks
Secondary Outcomes (14)
Forced vital capacity (FVC)
up to 4 weeks
Forced expiratory flow at 50 % FVC(FEF50%)
up to 4 weeks
Fractional exhaled nitric oxide (FENO)
up to 4 weeks
Total lung capacity (TLC)
up to 4 weeks
Specific airway resistance (sRAW)
up to 4 weeks
- +9 more secondary outcomes
Eligibility Criteria
Subjects referred to Klinikk for allergi og luftveissykdommer
You may qualify if:
- Referred to Klinikk for allergi og luftveissykdommer
- Meet at least 3 out of 5 criteria (symptoms related to exercise):
- Cough during exercise or within 5 minutes after exercise
- Wheeze during exercise or within 5 minutes after exercise
- Heavy breathing, expiratory in particular, during exercise or within 5 minutes after exercise (duration 5 minutes or more)
- Improvement of physical fitness/breath is lacking despite of exercise intensification
- Chest tightness during or after exercise
- Patients former diagnosed with-and treated for asthma who have symptoms of EIB are included in the study.
You may not qualify if:
- Ongoing respiratory infection or recent respiratory infection, judged by the responsible doctor to be of importance of the result
- The inability to perform an Exercise challenge test with maximum effort
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Klinikk for allergi og luftveissykdommer
Oslo, Ullevål, 0855, Norway
Related Publications (1)
Angell MR, Augestad LB, Haugen TS, Frostad A, Grønnerød TA, Stensrud T. Exercise-induced bronchoconstriction diagnostics: Impact of a repeated exercise challenge test. Open Journal of Respiratory Diseases 4:55-63, 2014 http://file.scirp.org/pdf/OJRD_2014043017202072.pdf
RESULT
Study Officials
- PRINCIPAL INVESTIGATOR
Liv B Augestad, Professor
Norwegian University of Science and Technology
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 23, 2010
First Posted
October 5, 2010
Study Start
August 1, 2010
Primary Completion
March 1, 2011
Study Completion
March 1, 2011
Last Updated
February 9, 2017
Record last verified: 2017-02