NCT01213706|CompletedResults
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Sponsor study identifier
interventional
45
1 country
1
Study Start
October 2009
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
January 2011
Actual (reported)Study Completion
May 2011
Actual (reported)In the present proposal the investigators wish to assess the effect of a single session with the device known as Exer-Rest® which applies Whole Body Periodic Acceleration (WBPA) on baseline airway blood flow (Qaw) and in Qaw variation, in current smokers, glucocorticoid-naïve asthmatics, and age-matched healthy never-smokers, with the expectation that the treatment will transiently increase the Qaw, and to a greater extent in the current smokers and patients with asthma who have endothelial dysfunction.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 2011
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 2009
Date type not reportedThis date has not been verified as actual or estimated.
October 1, 2010
Actual (reported)October 4, 2010
Actual (reported)January 2011
Actual (reported)May 2011
Actual (reported)September 12, 2014
Actual (reported)Airway Blood Flow Response to Albuterol
Airway Blood Flow will be measured before and 15 minutes after the 180 mcg of albuterol inhalation.
Qaw post minus Qaw pre albuterol after WBPA or Sham WBPA
All subjects will be performing this procedure. WBPA in spinal axis (pGz) will be administered with a platform that resembles a bed. The platform moves in a repetitive head-to-foot direction at 140 times a minute, producing 0.22 g.
Sham WBPA : All subjects will be performing this procedure before the WBPA. The subjects will rest for 45 minutes in the Whole Body Periodic Acceleration (WBPA) platform without movement as a control challenge.
Subjects will undergo to the Whole Body Periodic Acceleration platform for treatment (shaking period) for 45 min.
The subjects will rest for 45 minutes in the Whole Body Periodic Acceleration (WBPA) platform without movement as a control challenge.
Pulmonary Human Research Laboratory, University of Miami Miller School of Medicine
Miami, Florida, 33136, United States
Sackner MA, Gummels E, Adams JA. Nitric oxide is released into circulation with whole-body, periodic acceleration. Chest. 2005 Jan;127(1):30-9. doi: 10.1378/chest.127.1.30.
Sackner MA, Gummels E, Adams JA. Effect of moderate-intensity exercise, whole-body periodic acceleration, and passive cycling on nitric oxide release into circulation. Chest. 2005 Oct;128(4):2794-803. doi: 10.1378/chest.128.4.2794.
Adam Wanner, MD
University of Miami
45 participants (actual enrollment reported by the registry).
First Submitted
October 1, 2010
First Posted
October 4, 2010
Study Start
October 2009
Date type not reportedThis date has not been verified as actual or estimated.
HealthSpark 2: Improving Asthma Care for Preschool Children
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Matsumoto T, Fujita M, Tarutani Y, Yamane T, Takashima H, Nakae I, Horie M. Whole-body periodic acceleration enhances brachial endothelial function. Circ J. 2008 Jan;72(1):139-43. doi: 10.1253/circj.72.139.
Primary Completion
January 2011
Actual (reported)Study Completion
May 2011
Actual (reported)Last Updated
August 10, 2016
Results First Posted
September 12, 2014
Record last verified: 2016-07
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Source: ClinicalTrials.gov.
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