NCT01211015

Brief Summary

Aim: To investigate whether ER stress is implicated in the pathogenesis of various pulmonary disorders Measurement:

  1. 1.Unfolded protein responses (UPRs) in blood (PBMCs)of patients
  2. 2.CHOP
  3. 3.GRP 78 and so on
  4. 4.Unfolded protein responses (UPRs) in blood (PBMCs)of healthy controls
  5. 5.CHOP
  6. 6.GRP 78 and so on

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2010

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 28, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 29, 2010

Completed
Last Updated

September 29, 2010

Status Verified

September 1, 2010

First QC Date

September 28, 2010

Last Update Submit

September 28, 2010

Conditions

ER Stress,Chronic Airway Disorders,Lung Cancer,Interstitial Lung Diseases

Study Arms (2)

Control group

healthy control group

Disease group

asthma, COPD, ILD, lung malignancy

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

1. Control group * healthy control (volunteer) 2. Disease group * chronic pulmonary lung diseases including asthma, COPD, ILD, and lung cancer

You may qualify if:

  • \> 18 yrs
  • Definitive diagnosis as chronic pulmonary diseases by physician

You may not qualify if:

  • Any other chronic medical illness such as DM, HTN, and other malignancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chonbuk National University Hospital

Jeonju, Jeollabuk-do, 561-180, South Korea

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

blood

MeSH Terms

Conditions

Lung NeoplasmsLung Diseases, Interstitial

Condition Hierarchy (Ancestors)

Respiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Central Study Contacts

Yong Chul Lee, MD, phD

CONTACT

82-63-250-1664leeyc@chonbuk.ac.kr

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 28, 2010

First Posted

September 29, 2010

Study Start

July 1, 2010

Last Updated

September 29, 2010

Record last verified: 2010-09

Locations

KR(1)