Developing and Evaluating Interventions to Reduce Inappropriate Prescribing of Antibiotics in Primary Care

NCT01206738 | Completed Results

• 2 other identifiers: 2010PS10CZH/4/610
• Study Type: interventional
• Target: 270
• Locations: 1 country
• Sites: 1

Brief Summary

1. 1.Do paper-based and web-based intervention modelling experiments (the methodology we are developing) identify the same predictors of GP behaviour regarding prescribing of antibiotics for upper respiratory tract infections?
2. 2.Can a web-based IME system provide trialists with richer and more predictive information upon which to base the development of behavioural change interventions than paper-based IME systems?

Conditions

Antibiotic Prescribing by GPs for URTI

Outcome Measures

Primary Outcomes (2)

• Number of Simulated Scenarios Where an Antibiotic Was Not Prescribed

  Eight simulated clinical scenarios where presented to the GP and he/she was asked whether an antibiotic should be prescribed. The outcome measures was the number of scenarios where an antibiotic was not prescribed.

  Immediately after completion of questionnaire

• Email vs Postal Recruitment: Number of GPs Completing the First Questionnaire

  GPs were randomly allocated to receive their invitation to take part by email or by post. Outcome measure was proportion of GPs responding by completing the first questionnaire

  27/1/20111 - 15/5/2011

Study Arms (3)

Persuasive communication

EXPERIMENTAL

The persuasive intervention aimed to reinforce the GP's beliefs about the positive consequences of managing sore throat without prescribing antibiotics.

Behavioral: Persuasive communication

Alternative intervention

EXPERIMENTAL

This intervention was an action plan, supporting the GP to deal with two difficult prescribing situations: 1) a distressed patient (or often distressed parent of a child patient) 2) a patient demanding an antibiotic

Behavioral: Action plan

General information

ACTIVE COMPARATOR

No additional information was provided; the general information was the information already available to GPs about antibiotic prescribing.

Behavioral: General intervention

Interventions

Persuasive communication BEHAVIORAL

The persuasive intervention aimed to reinforce the GP's beliefs about the positive consequences of managing sore throat without prescribing antibiotics.

Persuasive communication

Action plan BEHAVIORAL

This intervention was an action plan, supporting the GP to deal with two difficult prescribing situations: 1) a distressed patient (or often distressed parent of a child patient) 2) a patient demanding an antibiotic

Alternative intervention

General intervention BEHAVIORAL

No additional information was provided; the general information was the information already available to GPs about antibiotic prescribing.

General information

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• GPs in Scotland.

You may not qualify if:

• Unable to obtain both an email address and a postal address for the GP.

Sponsors & Collaborators

• University of Dundee: lead
• University of Aberdeen: collaborator
• Newcastle University: collaborator
• University of Southampton: collaborator
• Chief Scientist Office of the Scottish Government: collaborator
• Scottish Primary Care Research Network: collaborator
• Scottish School of Primary Care: collaborator

Study Sites (1)

University of Dundee

Dundee, Tayside, DD1 4HN, United Kingdom

Location

Related Publications (4)

• Treweek S, Ricketts IW, Francis J, Eccles M, Bonetti D, Pitts NB, Maclennan G, Sullivan F, Jones C, Weal M, Barnett K. Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections: a randomised controlled trial to compare paper-based and web-based modelling experiments. Implement Sci. 2011 Mar 3;6:16. doi: 10.1186/1748-5908-6-16.

  PMID: 21371323 BACKGROUND

• Treweek S, Barnett K, Maclennan G, Bonetti D, Eccles MP, Francis JJ, Jones C, Pitts NB, Ricketts IW, Weal M, Sullivan F. E-mail invitations to general practitioners were as effective as postal invitations and were more efficient. J Clin Epidemiol. 2012 Jul;65(7):793-7. doi: 10.1016/j.jclinepi.2011.11.010. Epub 2012 Feb 4.

  PMID: 22306007 RESULT

• Treweek S, Bonetti D, Maclennan G, Barnett K, Eccles MP, Jones C, Pitts NB, Ricketts IW, Sullivan F, Weal M, Francis JJ. Paper-based and web-based intervention modeling experiments identified the same predictors of general practitioners' antibiotic-prescribing behavior. J Clin Epidemiol. 2014 Mar;67(3):296-304. doi: 10.1016/j.jclinepi.2013.09.015. Epub 2013 Dec 31.

  PMID: 24388292 RESULT

• Treweek S, Francis JJ, Bonetti D, Barnett K, Eccles MP, Hudson J, Jones C, Pitts NB, Ricketts IW, Sullivan F, Weal M, MacLennan G. A primary care Web-based Intervention Modeling Experiment replicated behavior changes seen in earlier paper-based experiment. J Clin Epidemiol. 2016 Dec;80:116-122. doi: 10.1016/j.jclinepi.2016.07.008. Epub 2016 Jul 26.

  PMID: 27470610 RESULT

Results Point of Contact

• Title: Prof Shaun Treweek
• Organization: University of Aberdeen

streweek@mac.com

Study Officials

• Shaun Treweek, PhD

  University of Dundee

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Senior Lecturer

Study Record Dates

• First Submitted: September 21, 2010
• First Posted: September 22, 2010
• Study Start: November 1, 2010
• Primary Completion: May 1, 2012
• Study Completion: September 1, 2012
• Last Updated: June 2, 2017
• Results First Posted: March 18, 2014

Record last verified: 2017-05

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)