NCT01206374

Brief Summary

Vitiligo vulgaris is an autoimmune disorder that causes loss of pigmentation over the skin, hair and mucous membranes (e.g. lips, nose, genitals). While genes have been identified that are thought to be required for development of vitiligo, only 5-10% of relatives develop disease. The triggers for disease onset have not yet been identified. The intent of this study is to research trends in laboratory data, social and medical history that may be contributory to vitiligo onset, location of disease, course of illness and response to therapy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
57

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Aug 2010

Longer than P75 for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2010

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

September 20, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 21, 2010

Completed
10 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2010

Completed
3.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2014

Completed
Last Updated

May 25, 2015

Status Verified

May 1, 2015

Enrollment Period

2 months

First QC Date

September 20, 2010

Last Update Submit

May 22, 2015

Conditions

Keywords

Vitiligo Vulgaris

Outcome Measures

Primary Outcomes (1)

  • Quality of life disturbances in people with vitiligo

    dermatology life quality indices were you used and correlated with location of disease

    point prevalence

Secondary Outcomes (1)

  • self-reporting of vitiligo disease symptoms and history

    single survey

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients willing to sign consent, complete questionnaire and/ or laboratory studies.

You may qualify if:

  • Diagnosis of Vitiligo Vulgaris
  • Ability to sign consent

You may not qualify if:

  • Pregnant
  • Inability to sign consent
  • Inability to complete questionnaire

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Department of Dermatology, Beth Israel Medical Center

New York, New York, 10003, United States

Location

Department of Dermatology, St. Luke's-Roosevelt Hospital Center

New York, New York, 10025, United States

Location

Related Publications (3)

  • Silverberg NB. Update on childhood vitiligo. Curr Opin Pediatr. 2010 Aug;22(4):445-52. doi: 10.1097/MOP.0b013e32833b6ac3.

    PMID: 20616733BACKGROUND
  • Silverberg JI, Silverberg AI, Malka E, Silverberg NB. A pilot study assessing the role of 25 hydroxy vitamin D levels in patients with vitiligo vulgaris. J Am Acad Dermatol. 2010 Jun;62(6):937-41. doi: 10.1016/j.jaad.2009.11.024.

    PMID: 20466170BACKGROUND
  • Pagovich OE, Silverberg JI, Freilich E, Silverberg NB. Thyroid abnormalities in pediatric patients with vitiligo in New York City. Cutis. 2008 Jun;81(6):463-6.

    PMID: 18666385BACKGROUND

MeSH Terms

Conditions

Vitiligo

Condition Hierarchy (Ancestors)

HypopigmentationPigmentation DisordersSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Nanette Silverberg, MD

    StLukesNY

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 20, 2010

First Posted

September 21, 2010

Study Start

August 1, 2010

Primary Completion

October 1, 2010

Study Completion

September 1, 2014

Last Updated

May 25, 2015

Record last verified: 2015-05

Locations