Reduction of Nosocomial Vancomycin -Resistant Enterococci (VRE) Colonization and Infection by Active Surveillance and Intervention of Infection Control

NCT01201031 | Completed

• 1 other identifier: 98105
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Vancomycin -resistant enterococci(VRE) has emerged as one of the most common nosocomial pathogen of health-care associated infection since 1988. Although the new antimicrobial agents such as Tigecycline , Daptomycin, Linezolid have clinically effectiveness for the treatment of VRE, but there was not appropriate drugs for eradicating the colonization of VRE. So the active surveillance and strict contact precaution are the best methods for VRE colonization and transmission. This is a one year study program, we select a unit as the study site. First month (January) is the prepare period. Therefore , we collect 3 months (from February to April) baseline data, then interrupted one month(May) for the health care worker's infection control education. Then the intervention period are three months (from June to August), and the last four months(from September to December) are the analysis and evaluation period. In the baseline period, we only do the patient's active surveillance and environmental culture. In the intervention period, beside the patient's active surveillance and environmental culture, we add contact precaution as the infection control method. If patient has VRE infection, we prescribe appropriate antibiotic therapy until the culture result proved no growth of VRE. The aim of this study is to compare and analyze these two period (baseline period and intervention period) for understanding the transmission, risk factors and carriage rate of VRE, as the important guidelines for the VRE infection control in the future.

Conditions

Infection

Keywords

for the active surveillance of VRE colinization and infection

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients admitted to RCC unit , and these patients received active surveillance of VRE colinization

You may qualify if:

• all patients admitted to RCC unit

You may not qualify if:

• if the patients or family refused the exam of anal swab .

Sponsors & Collaborators

• Taipei Medical University WanFang Hospital: lead

Study Sites (1)

Taipei Medical University-WanFang Hospital

Taipei, Taiwan

Location

MeSH Terms

Conditions

Infections

Study Officials

• Wen-Sen Lee

  Taipei Medical University WanFang Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 12, 2010
• First Posted: September 14, 2010
• Study Start: April 1, 2010
• Primary Completion: September 1, 2010
• Study Completion: February 1, 2011
• Last Updated: March 16, 2011

Record last verified: 2011-03

Locations

TW (1)