NCT01198483

Brief Summary

The purpose of this study is to compare refractive outcomes after two different types of combined cataract surgery, namely microinscision cataract surgery and smallincision cataract surgery, and sutureless 23-gauge vitrectomy in patients presenting with vitreoretinal disorders and coexisting cataracts.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2011

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 7, 2010

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 10, 2010

Completed
11 months until next milestone

Study Start

First participant enrolled

August 1, 2011

Completed
6.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2017

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2018

Completed
Last Updated

September 7, 2016

Status Verified

September 1, 2016

Enrollment Period

6.3 years

First QC Date

September 7, 2010

Last Update Submit

September 3, 2016

Conditions

Keywords

refractionrefractive errorcombined surgerymicroincisionsmallincisioncataract surgeryvitrectomy

Outcome Measures

Primary Outcomes (1)

  • Refractive outcome

    Refractive outcome includes autorefraction using Humphrey Automatic Refractor/Keratometer(Carl Zeiss AG, Oberkochen, Germany) and subjective manifest refraction.

    12 weeks after surgery

Secondary Outcomes (3)

  • measurements of anterior chamber depth (ACD)

    12 weeks after surgery

  • intraocular pressure (IOP)

    12 weeks after surgery

  • functional outcome

    12 weeks after surgery

Study Arms (2)

Micro

ACTIVE COMPARATOR

Microincision cataract surgery

Procedure: Combined Micro- Surgery

Small

ACTIVE COMPARATOR

Smallincision cataract surgery

Procedure: Combined Small-Surgery

Interventions

Microincision Cataract Surgery combined with 23-gauge/25-gauge/27 gauge Vitrectomy

Micro

Smallincision cataract surgery combined with 23 gauge vitrectomy

Small

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • diagnosis vitreoretinal disorder with coexisting cataract
  • combined surgery
  • age over 60 years
  • IOL master for preoperative intraocularlens (IOL) calculation

You may not qualify if:

  • ultrasound for IOL calculation due to hazy media (dense cataract,vitreous hemorrhage)
  • macular edema, proliferative diabetic retinopathy
  • myopia or hyperopia more than 5 diopters, astigmatism more than 2 diopters
  • previous refractive surgery, retinal detachment surgery, glaucoma surgery and vitrectomy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Rudolf Foundation Clinic

Vienna, 1030, Austria

RECRUITING

MeSH Terms

Conditions

Refractive Errors

Condition Hierarchy (Ancestors)

Eye Diseases

Study Officials

  • Susanne Binder, Univ.Prof.Dr.

    Ludwig Boltzmann Institute of Retinology and biomicroscopic Lasersurgery

    PRINCIPAL INVESTIGATOR
  • Christiane I Falkner-Radler, M.D.

    Ludwig Boltzmann Institut of Retinology and biomicroscopic Lasersurgery

    STUDY CHAIR

Central Study Contacts

Christiane I Falkner-Radler, MD

CONTACT

Katharina Krepler, Priv.Doz.Dr.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

September 7, 2010

First Posted

September 10, 2010

Study Start

August 1, 2011

Primary Completion

December 1, 2017

Study Completion

December 1, 2018

Last Updated

September 7, 2016

Record last verified: 2016-09

Locations