Thoracic Outlet Syndrome: Case Reports and Analysis With Ultrasound Imaging

NCT01196637 | Completed

• 1 other identifier: TOS-US BP JAOA
• Study Type: observational
• Target: 6
• Locations: 1 country
• Sites: 1

Brief Summary

Thoracic outlet syndrome is caused by compression of the brachial plexus, in most cases under the pectoralis minor muscle in the infraclavicular region of the shoulder. The hypothesis is that ultrasound imaging can be used to visualize brachial plexus compression and distortion of the pectoralis muscle during arm activity, such as abduction, and that normal subjects will not demonstrate any plexus compression or muscle distortion.

Conditions

Thoracic Outlet Syndrome

Keywords

thoracic outlet syndrome; brachial plexopathy; ultrasonography

Outcome Measures

Primary Outcomes (1)

• Brachial plexus compression on ultrasound imaging in thoracic outlet syndrome patients

  4 months

Secondary Outcomes (1)

• No brachial plexus compression in normal subjects

  4 months

Study Arms (2)

Thoracic outlet syndrome

These patients have documented thoracic outlet syndrome

Normal Subjects

These patients have no thoracic outlet syndrome

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients with upper limb symptoms of pain, numbness, tingling, or weakness, aggravated by arm abduction; Adult patients with no upper limb symptoms

You may qualify if:

• Thoracic outlet patients must have:
• symptoms consistent with thoracic outlet syndrome, and
• no electrical testing abnormality, and
• positive arm abduction stress tests.
• Normal subjects must have:
• no upper limb symptoms, or
• normal nerve testing, and
• negative arm abduction stress test

You may not qualify if:

• Thoracic outlet patients excluded if they have:
• nerve test abnormalities, or
• negative arm abduction stress test
• Normals excluded if they have:
• abnormalities on nerve testing, or
• positive arm abduction stress tests

Sponsors & Collaborators

• EMG Labs of Arizona Arthritis & Rheumatology Associates: lead

Study Sites (1)

EMG Labs of AARA

Paradise Valley, Arizona, 85253, United States

Location

MeSH Terms

Conditions

Thoracic Outlet Syndrome; Brachial Plexus Neuropathies

Condition Hierarchy (Ancestors)

Nerve Compression Syndromes; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Benjamin M Sucher, D.O.

  EMG Labs of AARA

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 5, 2010
• First Posted: September 8, 2010
• Study Start: June 1, 2010
• Primary Completion: September 1, 2010
• Study Completion: September 1, 2010
• Last Updated: September 9, 2010

Record last verified: 2010-09

Locations

US (1)