NCT01195402

Brief Summary

This randomised-controlled study is undertaken to investigate the effects of a long term low intensity outpatient training program on physical fitness and quality of life in moderate to severe COPD patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Apr 2004

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2004

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2005

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2006

Completed
4.6 years until next milestone

First Submitted

Initial submission to the registry

September 2, 2010

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 6, 2010

Completed
Last Updated

September 6, 2010

Status Verified

September 1, 2010

Enrollment Period

1.7 years

First QC Date

September 2, 2010

Last Update Submit

September 3, 2010

Conditions

Keywords

COPDpulmonary rehabilitation

Outcome Measures

Primary Outcomes (1)

  • 6-Minute walk distance

    Six months

Secondary Outcomes (2)

  • Quality of life

    Six months

  • Maximum oxygen uptake

    Six months

Study Arms (2)

Control

NO INTERVENTION

Subjects do not receive any kind of active intervention.

pulmonary outpatient rehabilitation

ACTIVE COMPARATOR

Subjects participate in an outpatient pulmonary rehabilitation program

Procedure: pulmonary outpatient rehabilitation

Interventions

Subjects take part in once weekly training sessions of 60 min duration. Sessions take place in local physiotherapist practice and involve simple training devices (chairs, elastic bands, balls). In addition, subjects take part in a structured and validated educational program concerning COPD (COBRA) of 8 h duration. They are offered counselling regarding nutrition (2 h), psycho-social (2 h) and social (2 h) aspects.

pulmonary outpatient rehabilitation

Eligibility Criteria

Age50 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • COPD GOLD stage II-IV
  • smoking history of \>20 pack years
  • adequate pharmacological therapy
  • written informed consent

You may not qualify if:

  • respiratory insufficiency, defined as PaO2\<55 mm Hg and/or PaCO2\>50 mm Hg breathing room air
  • manifest cardiac insufficiency
  • uncontrolled arterial hypertension
  • malignant disease
  • symptomatic coronary heart disease resp. pathological cycle ergometry results
  • limited physical capabilities caused by musculoskeletal disorders
  • unwillingness to return for follow-up
  • previous or ongoing participation in exercise training programs
  • unability to attend at least 75% of sessions

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Medical Center Hamburg-Eppendorf

Hamburg, 20246, Germany

Location

Related Publications (1)

  • Baumann HJ, Kluge S, Rummel K, Klose H, Hennigs JK, Schmoller T, Meyer A. Low intensity, long-term outpatient rehabilitation in COPD: a randomised controlled trial. Respir Res. 2012 Sep 27;13(1):86. doi: 10.1186/1465-9921-13-86.

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Andreas Meyer, M.D.

    Kliniken Mariahilf GmbH, Mönchengladbach, Germany

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 2, 2010

First Posted

September 6, 2010

Study Start

April 1, 2004

Primary Completion

December 1, 2005

Study Completion

February 1, 2006

Last Updated

September 6, 2010

Record last verified: 2010-09

Locations