NCT01184690

Brief Summary

Double-balloon endoscopy (DBE) is a new device that allows diagnosis and treatment throughout the entire small intestine. Although the originally described method requires two operators, the investigators have recently developed a method to perform DBE by a single operator. The investigators here assessed the clinical usefulness of this one-person method in comparison to the conventional two-person DBE.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Aug 2010

Shorter than P25 for phase_4

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2010

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

August 16, 2010

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 19, 2010

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2011

Completed
Last Updated

August 19, 2010

Status Verified

August 1, 2010

Enrollment Period

1 year

First QC Date

August 16, 2010

Last Update Submit

August 18, 2010

Conditions

Keywords

double-balloon endoscopydiagnostic yield

Outcome Measures

Primary Outcomes (2)

  • completion whether the complete enteroscopy is achieved?

    The completion rate for examination of the entire small intestine

    2 hours

  • lesion-discovery

    lesion-discovery rate

    2 hours

Secondary Outcomes (2)

  • observation time

    2 hours

  • Number of Participants with Adverse Events

    2 days

Study Arms (2)

Single-operator DBE

ACTIVE COMPARATOR

Single-operator double-balloon endoscopy

Procedure: Single-operator double-balloon endoscopy

Dual-operator DBE

ACTIVE COMPARATOR

Dual-operator double-balloon endoscopy

Procedure: dual-operator double-balloon endoscopy

Interventions

Single-operator double-balloon endoscopy

Single-operator DBE

dual-operator double-balloon endoscopy

Dual-operator DBE

Eligibility Criteria

Age16 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • suspected or known small-bowel disease
  • age: 16-70

You may not qualify if:

  • pregnancy
  • coagulation disorders
  • prior surgery of the small bowel and colon

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shanghai changzheng Hospital

Shanghai, Shanghai Municipality, 200003, China

Location

Related Publications (2)

  • Araki A, Tsuchiya K, Okada E, Suzuki S, Oshima S, Okamoto R, Kanai T, Watanabe M. Single-operator method for double-balloon endoscopy: a pilot study. Endoscopy. 2008 Nov;40(11):936-8. doi: 10.1055/s-2008-1077545. Epub 2008 Sep 25.

  • Araki A, Tsuchiya K, Okada E, Suzuki S, Oshima S, Yoshioka S, Yoshioka A, Kanai T, Watanabe M. Single-operator double-balloon endoscopy (DBE) is as effective as dual-operator DBE. J Gastroenterol Hepatol. 2009 May;24(5):770-5. doi: 10.1111/j.1440-1746.2009.05787.x. Epub 2009 Feb 12.

Study Officials

  • Jian Shi, MD

    Shanghai Changzheng Hospital

    PRINCIPAL INVESTIGATOR
  • Bin Shi, MD

    Shanghai Changzheng Hospital

    PRINCIPAL INVESTIGATOR
  • Wei-Fen Xie, MD

    Shanghai Changzheng Hospital

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 16, 2010

First Posted

August 19, 2010

Study Start

August 1, 2010

Primary Completion

August 1, 2011

Study Completion

August 1, 2011

Last Updated

August 19, 2010

Record last verified: 2010-08

Locations