NCT01184378

Brief Summary

The great majority of infants formula contain fats exclusively from vegetable oil. Nevertheless, the use of both vegetable and dairy lipids is on a real interest to obtain an infant formula closer to the nutritional composition of maternal milk.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for phase_2

Timeline
Completed

Started Nov 2008

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2008

Completed
1.8 years until next milestone

First Submitted

Initial submission to the registry

August 17, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 18, 2010

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2010

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2011

Completed
Last Updated

January 26, 2011

Status Verified

January 1, 2011

Enrollment Period

2.1 years

First QC Date

August 17, 2010

Last Update Submit

January 25, 2011

Conditions

Keywords

infant formuladairy fatsoluble milk protein

Outcome Measures

Primary Outcomes (1)

  • digestibility of lipids in formula

    lipid content determination in feces during a 3 days period of collection after 15d and 30d of formula intake

    during the 30d consumption period

Secondary Outcomes (1)

  • tolerance and growth

    during the 30d of formula intake

Study Arms (2)

control formula

PLACEBO COMPARATOR

formula containing only vegetable fats

Dietary Supplement: dairy lipids and soluble milk proteins

new formula

EXPERIMENTAL

new formula with dairy lipids and soluble milk proteins

Dietary Supplement: dairy lipids and soluble milk proteins

Interventions

one month formula supplementation feces are collected during a 3 days period after 15 and 30 days of formula intake

control formulanew formula

Eligibility Criteria

Age2 Months - 4 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • normal growth;
  • considered as healthy by the investigator according to the medical interrogation and the clinical examination;
  • receiving exclusively infant formula for at least 15 days.
  • without any solid food during the month of the study

You may not qualify if:

  • Premature born children or small born weights;
  • Children breast-fed or weaned for less than 15 days;
  • Children with solid food
  • Food allergy, particularly in milk proteins allergy , and lactose intolerance ;
  • Tumoral, inflammatory, cardiac, lung, renal, digestive diseases(syndrome of malabsorption);
  • Children under medical treatment (ex: paracetamol).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Faculté de Médecine

Dijon, 21078, France

Location

Hopital Mère-Enfants

Rennes, 35000, France

Location

MeSH Terms

Conditions

Steatorrhea

Condition Hierarchy (Ancestors)

Malabsorption SyndromesIntestinal DiseasesGastrointestinal DiseasesDigestive System DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

August 17, 2010

First Posted

August 18, 2010

Study Start

November 1, 2008

Primary Completion

December 1, 2010

Study Completion

January 1, 2011

Last Updated

January 26, 2011

Record last verified: 2011-01

Locations