NCT01183039

Brief Summary

The purpose of this study is to understand underlying mechanisms of improved exercise tolerance in Healthy Sedentary Subjects after training program.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2008

Typical duration for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2008

Completed
2.3 years until next milestone

First Submitted

Initial submission to the registry

August 16, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 17, 2010

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2010

Completed
Last Updated

September 5, 2012

Status Verified

September 1, 2012

Enrollment Period

2.6 years

First QC Date

August 16, 2010

Last Update Submit

September 3, 2012

Conditions

Sedentary Subjects

Keywords

Sedentary

Outcome Measures

Primary Outcomes (1)

  • Effects of training program on mitochondrial function and oxidative stress

    6 to 8 weeks

Secondary Outcomes (1)

  • Relationship between mitochondrial function, oxidative stress and exercise tolerance in COPD patients

    6 to 8 weeks

Study Arms (2)

Ventilatory threshold

ACTIVE COMPARATOR

Training at the ventilatory threshold

Other: Training

Metabolic threshold

ACTIVE COMPARATOR

Training at the metabolic threshold

Other: Training

Interventions

TrainingOTHER

20 sessions of training

Also known as: Vt, Mt
Metabolic thresholdVentilatory threshold

Eligibility Criteria

Age50 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • healthy Sedentary Subjects

You may not qualify if:

  • neuromuscular disease
  • chronic heart failure
  • diabetes
  • renal diseases
  • liver diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Clinique du souffle La valonie

Lodève, France

Location

hopital Arnaud de Vilneuve

Montpellier, France

Location

Clinique du souffle La solane

Osséja, France

Location

MeSH Terms

Conditions

Sedentary Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Maurice MH Hayot, MCU-PH

    Institut National de la Santé Et de la Recherche Médicale, France

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 16, 2010

First Posted

August 17, 2010

Study Start

May 1, 2008

Primary Completion

December 1, 2010

Study Completion

December 1, 2010

Last Updated

September 5, 2012

Record last verified: 2012-09

Locations

FR(3)