NCT01180491

Brief Summary

The purpose of this study is to further evaluate and document early visible effects on nail appearance of topical K101.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
75

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2010

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 10, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 12, 2010

Completed
20 days until next milestone

Study Start

First participant enrolled

September 1, 2010

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2010

Completed
Last Updated

June 26, 2013

Status Verified

June 1, 2013

Enrollment Period

2 months

First QC Date

August 10, 2010

Last Update Submit

June 25, 2013

Conditions

Keywords

Discoloured and deformed nails resulting from onychomycosis

Outcome Measures

Primary Outcomes (1)

  • Proportion of patients experiencing at least some improvement of the target nail (scoring 2 or more according to Global Assessment Scale) after 8 weeks treatment.

Interventions

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male or female patients aged 18 years or older
  • %-75% of the target nail altered as a result of onychomycosis
  • Signed written informed consent

You may not qualify if:

  • Proximal subungual onychomycosis
  • Patient who has been previously randomized to treatment in the phase III study K70-2 investigating K101
  • Other conditions known to cause abnormal nail appearance
  • Use of topical (1 month before screening) and/or systemic (3 months before screening) antifungal medication.
  • Participation in another clinical study with an investigational drug or device during the previous 4 weeks before enrolment.
  • Known allergy to any of the tested treatment products

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Onychomycosis

Condition Hierarchy (Ancestors)

TineaDermatomycosesMycosesBacterial Infections and MycosesInfectionsSkin Diseases, InfectiousNail DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Study Design

Study Type
interventional
Phase
not applicable
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 10, 2010

First Posted

August 12, 2010

Study Start

September 1, 2010

Primary Completion

November 1, 2010

Study Completion

November 1, 2010

Last Updated

June 26, 2013

Record last verified: 2013-06