NCT01178723

Brief Summary

Studies has found a connection between breakfast consumption and obesity and obesity-related complications, but only few studies examined the effect of breakfast size. The purpose of this study is to examine the effect of breakfast size on several parameters in adults with Type 2 diabetes mellitus.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for not_applicable diabetes-mellitus-type-2

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 8, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 10, 2010

Completed
Last Updated

August 10, 2010

Status Verified

August 1, 2010

First QC Date

August 8, 2010

Last Update Submit

August 8, 2010

Conditions

Keywords

breakfast sizeblood glucose balancehormonal profileappetite hormonesadipokinespro-inflammatory cytokines

Outcome Measures

Primary Outcomes (1)

  • blood glucose balance

    HBA1C, C-peptid, insulin, glucose, HOMA-IR, Glycomark

    three months

Secondary Outcomes (4)

  • anthropometric parameters

    three months

  • Adipokines and hormones

    three months

  • pro-inflammatory cytokines

    three months

  • lipid profile

    three months

Interventions

breakfast sizeDIETARY_SUPPLEMENT

The research group will receive instructions to eat a large breakfast, Dividing the total daily calories recommended to the patient to: breakfast - 1/8 of the total daily calories , lunch - 1/3 of the total daily calories and supper- 1/3 of the total daily calories. (the rest of the calories will be snacks between the meals) In contrast, the control group that will receive instructions to eat a small breakfast. Dividing the total daily calories recommended to the patient to: breakfast - 1/3 of the total daily calories , lunch - 1/4 of the total daily calories and supper- 1/4 of the total daily calories (the rest of the calories will snacks between the meals). The instructions will be adapted to each patient individually

Eligibility Criteria

Age30 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Men and women ages: 30-70
  • Type 2 diabetics who are treated on a diet and / or pills
  • Patients who receive a stable drug treatment (no change in the type/dosage of drugs during the three months preceding the research)
  • Obese or overweight (35\> BMI\> 25)
  • Patients who did not participate in another research for at least 30 days
  • Patients who agree to sign a consent form and participate in research
  • Patients with high compliance.

You may not qualify if:

  • Patients under the age 30 or over 70
  • Type 1 I diabetics
  • Patients who are insulin dependent
  • Type 2 diabetics who are treated with injections
  • BMI less than 25 or BMI over 35
  • Patients who had Bariatric surgery
  • Patients with food absorption disorders
  • Active malignant disease
  • Thyroid function disorder
  • Active psychiatric illness
  • Pregnancy / breastfeeding

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Diabetes Unit, Wolfson Medical Center

Holon, 58100, Israel

Location

Diabetes Unit, Wolfson Medical Center

Holon, 58100, Israel

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

August 8, 2010

First Posted

August 10, 2010

Last Updated

August 10, 2010

Record last verified: 2010-08

Locations