Sonographic Differences in Brain Measurements Between Normal and Intrauterine Growth Restriction (IUGR) Fetuses

NCT01178619 | Withdrawn

• 1 other identifier: MMC10095-2010CTIL
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

Intrauterine growth restriction is being suspected in cases where the fetal estimated weight is less then the 10 th percentile for its gestational age. Abdominal circumference is the most influenced measurement in this cases. Head circumference on the other hand can be or not be influenced. Previous studies have shown that transverse cerebellar diameter (TCD) is constant to gestational age and is not influenced by IUGR.Other showed lower TCD in IUGR fetuses. We would like to study the differences in cerebellar, vermian and corpus callosum growth between normal to IUGR fetuses and between symmetrical and asymmetrical IUGR. In this observational study we will include pregnant women between 28-37 gestational week with a singleton otherwise normal pregnancies. We will measure the fetal TCD, vermian distances and the CC, abdominal circumference, head circumference and femur length. we will compeer these measurements according to the following groups:normal fetuses, symmetrical and asymmetrical IUGR.

Conditions

Intra-uterine Growth Restriction

Keywords

IUGR fetuses; symmetrical IUGR; asymmetrical IUGR

Study Arms (3)

AGA

symmetrical IUGR

asymmetrical IUGR

Eligibility Criteria

• Age: 28 Weeks - 37 Weeks
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

pregnant women 28-37 GA, singleton, otherwise normal fetuses

You may qualify if:

• singleton,
• GA,
• well dated pregnancy.

You may not qualify if:

• multifetal pregnancies,
• no first trimester dating,
• fetuses with known chromosomal or structural anomalies.

Sponsors & Collaborators

• Meir Medical Center: lead

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 8, 2010
• First Posted: August 10, 2010
• Study Start: September 1, 2010
• Primary Completion: August 1, 2012
• Study Completion: August 1, 2012
• Last Updated: August 28, 2013

Record last verified: 2013-08