NCT01173250

Brief Summary

Total proctocolectomy with ileal pouch anal anastomosis is the first choice surgical operation for management of ulcerative colitis and familial adenomatous polyposis. The addition of diverting ileostomy may reduce septic complications. In this randomized study the investigators compare two groups of patients with stapled ileoanal pouch one of them had diverting ileostomy and in the other this step is omitted.

Trial Health

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 30, 2010

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 2, 2010

Completed
Last Updated

August 16, 2010

Status Verified

October 1, 2010

First QC Date

July 30, 2010

Last Update Submit

August 13, 2010

Conditions

Keywords

total proctocolectomy with ileal pouch anal anastomosis with and without ileostomy

Study Arms (2)

stapled ileoanal pouch without diverting ileostomy

ACTIVE COMPARATOR
Procedure: omitting diverting ileostomy

stapled ileoanal pouch with diverting ileostomy

PLACEBO COMPARATOR
Procedure: adding diverting ileostomy

Interventions

stapled ileoanal pouch with diverting ileostomy
stapled ileoanal pouch without diverting ileostomy

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • patients having total proctocolectomy with ileal pouch anal anastomosis.

You may not qualify if:

  • hypoalbuminemia
  • prolonged steroid use
  • anemia
  • anastomosis under tension
  • leak with air test
  • bleeding
  • poor vascular supply of anastomosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Colitis, UlcerativeAdenomatous Polyposis Coli

Condition Hierarchy (Ancestors)

ColitisGastroenteritisGastrointestinal DiseasesDigestive System DiseasesInflammatory Bowel DiseasesColonic DiseasesIntestinal DiseasesAdenomatous PolypsAdenomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasmsColorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplastic Syndromes, HereditaryIntestinal PolyposisGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

Study Type
interventional
Phase
not applicable
Sponsor Type
OTHER

Study Record Dates

First Submitted

July 30, 2010

First Posted

August 2, 2010

Last Updated

August 16, 2010

Record last verified: 2010-10