NCT01169974

Brief Summary

The investigators aim to test the hypothesis that Laser speckle contrast imaging allows for the measurement of cutaneous blood flow following various durations of tourniquet ischemia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
41

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Feb 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 23, 2010

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 26, 2010

Completed
6 months until next milestone

Study Start

First participant enrolled

February 1, 2011

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2012

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 4, 2012

Completed
Last Updated

November 1, 2017

Status Verified

October 1, 2017

Enrollment Period

1.6 years

First QC Date

July 23, 2010

Last Update Submit

October 30, 2017

Conditions

Microcirculation

Keywords

Microcirculationlaser flowmetrySkinPhysiology

Outcome Measures

Primary Outcomes (1)

  • Laser speckle

    Peak value of laser speckle signal

    with 2 minutes of ischemia

Study Arms (1)

healthy volunteers

Other: tourniquet ischemia

Interventions

tourniquet ischemiaOTHER

Recording of cutaneous blood flow on the forearm at rest before and following tourniquet ischemias of 1 , 2 \& 3 minutes

Also known as: Laser doppler flowmetry, Transcutaneous oxygen pressure, Near infra-red spectrometry, Plethysmography
healthy volunteers

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

healthy volunteers

You may qualify if:

  • Healthy volunteers
  • Affiliation to the French health system

You may not qualify if:

  • Any disease or chronic treatment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University hospital

Angers, France

Location

MeSH Terms

Interventions

Laser-Doppler FlowmetryBlood Gas Monitoring, Transcutaneous

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, CardiovascularDiagnostic Techniques and ProceduresDiagnosisRheologyInvestigative TechniquesOximetryBlood Gas AnalysisBlood Chemical AnalysisClinical Chemistry TestsClinical Laboratory TechniquesHeart Function TestsRespiratory Function TestsDiagnostic Techniques, Respiratory System

Study Officials

  • Guillaume Mahe

    University Hospital in Angers

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 23, 2010

First Posted

July 26, 2010

Study Start

February 1, 2011

Primary Completion

September 1, 2012

Study Completion

December 4, 2012

Last Updated

November 1, 2017

Record last verified: 2017-10

Locations

FR(1)