Stress Echo and Electric Impedance Tomography (EIT) Pilot Study

NCT01168557 | Completed

• 1 other identifier: Stress Echo - EIT
• Study Type: interventional
• Target: 8
• Locations: 1 country
• Sites: 1

Brief Summary

Electric Impedance Tomography (EIT) is a technique based on the injection of small currents and voltage measurements using electrodes on the skin surface generating cross-sectional images representing impedance change in a slice of the thorax.It is a radiation free, non- invasive and portable lung imaging technique. Impedance changes in lung ventilation as well as in lung perfusion can be shown. To investigate lung perfusion by EIT measurements, cardiac output measured by routinely undergone stress echocardiography at rest and stress are compared to parameters measured by EIT.

Conditions

Electric Impedance Tomography; Stress Echocardiography; Cardiac Output; Ventilation; Perfusion

Keywords

electric impedance tomography; stress-echocardiography; ventilation; perfusion

Outcome Measures

Primary Outcomes (1)

• influence of cardiac output on EIT measurements (feasibility)

  It will be investigated if a change in cardiac output, which is measured by stress-echocardiography by dobutamine, has an influence on the parameters determined by EIT measurements.

  single measurement of 45 minutes

Study Arms (1)

Stress-Echo and EIT

EXPERIMENTAL

Patients who routinely undergo stress-echocardiography will additionally be measured by EIT using a rubber belt, which will be placed around their chest

Device: EIT (Electrical Impedance Tomography)

Interventions

EIT (Electrical Impedance Tomography) DEVICE

EIT measurement; concomitant to stress echocardiography (about 45 minutes) EIT measurements (1 minute) are performed at rest, at low dobutamine stress, at peak and at relaxation

Stress-Echo and EIT

Eligibility Criteria

• Age: 18 Years+
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• male patients \>18 years who routinely have to undergo stress echocardiography
• ejection fraction \>50%
• able to give informed consent

You may not qualify if:

• restrictive lung diseases
• active implants and heart pace makers and implanted converter defibrillator
• foreign metallic objects in the thorax
• Not adequate quality of imaging of stress echocardiography

Sponsors & Collaborators

• RWTH Aachen University: lead

Study Sites (1)

Medical Clinic I, University Hospital Aachen

Aachen, North Rhine-Westphalia, 52074, Germany

Location

MeSH Terms

Conditions

Respiratory Aspiration

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Stefan Krueger, MD, Assoc. Prof.

  RWTH Aachen University of Cardiology, Pneumology and Angiology, Aachen, NRW, Germany

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 22, 2010
• First Posted: July 23, 2010
• Study Start: July 1, 2010
• Primary Completion: September 1, 2012
• Study Completion: September 1, 2012
• Last Updated: November 27, 2013

Record last verified: 2013-11

Locations

DE (1)