NCT01163981

Brief Summary

The investigators suspect that using ultrasound to guide insertion of needles for dialysis patients will make this process quicker and more accurate, thus reducing complications and reducing discomfort for patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
31

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2016

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 12, 2010

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 16, 2010

Completed
6.3 years until next milestone

Study Start

First participant enrolled

November 1, 2016

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2017

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2017

Completed
Last Updated

December 17, 2020

Status Verified

October 1, 2018

Enrollment Period

6 months

First QC Date

July 12, 2010

Last Update Submit

December 15, 2020

Conditions

Keywords

duplex UltrasoundHaemodialysisVascular Access

Outcome Measures

Primary Outcomes (1)

  • Time to establish dialysis

    Time to commence 2 needle dialysis from first palpation or imaging of fistula

    Within an average of 5 minutes into each of the next 12 consecutive dialysis session

Secondary Outcomes (4)

  • - Patient reported pain scores Patient reported anxiety and pain

    enrollment, two weeks and four weeks into trial

  • Number of cannulation attempts( skin punctures or passes of needle)

    Within an average of 5 minutes into each of the next 12 consecutive dialysis session

  • complications of needling

    Within 2 hours of completing each of the next 12 consecutive dialysis sessions

  • Referral for difficult needling during trial

    From enrollment to 24 hours following completion of the last of 12 consecutive dialysis sessions

Study Arms (2)

Blind cannulation

NO INTERVENTION

Cannulation without guidance

Ultrasound guided cannulation

EXPERIMENTAL

Ultrasound guided cannulation

Other: Use of ultrasound guidance in cannulation

Interventions

Use of guidance with duplex ultrasound to complete cannulation of dialysis access

Also known as: duplex ultrasound
Ultrasound guided cannulation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Dialysis 3X per week
  • Dialysing via 2 needles in fistula
  • No deviation from routine dialysis protocol (additional or no heparin etc)

You may not qualify if:

  • a. Active or recent fistula infection/thrombosis/intervention in 6/52 of study
  • Withdrawal criteria:
  • Patient request
  • Patient non compliance with study protocol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hull Royal Infirmary

Hull, East Yorkshire, HU3 2JZ, United Kingdom

Location

MeSH Terms

Interventions

Catheterization

Intervention Hierarchy (Ancestors)

TherapeuticsInvestigative Techniques

Study Officials

  • George E Smith, BSc MBBS MRCS

    Hull and East Yorkshire NHS Trust

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 12, 2010

First Posted

July 16, 2010

Study Start

November 1, 2016

Primary Completion

May 1, 2017

Study Completion

August 1, 2017

Last Updated

December 17, 2020

Record last verified: 2018-10

Locations