NCT01162525

Brief Summary

Percutaneous tibial nerve stimulation is introduced as regular treatment option for fecal urge continence at the Cantonal Hospital St. Gallen. During this introduction phase efficiency und adverse events will be monitored in this observational study.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
57

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2010

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2010

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

July 13, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

July 14, 2010

Completed
7.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2017

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2017

Completed
Last Updated

September 19, 2018

Status Verified

September 1, 2018

Enrollment Period

7.8 years

First QC Date

July 13, 2010

Last Update Submit

September 18, 2018

Conditions

Keywords

Fecal IncontinenceFecal Urge IncontinencePercutaneous tibial nerve stimulation

Outcome Measures

Primary Outcomes (3)

  • Fecal Incontinence

    Jorge Wexner Score (Dis Colon Rectum (1993) 36:77) compared to pretreatment * Score for fecal incontinence, with 5 items and score range of 0 - 20

    6 weeks

  • Fecal Incontinence

    Jorge Wexner Score (Dis Colon Rectum (1993) 36:77) compared to pretreatment * Score for fecal incontinence, with 5 items and score range of 0 - 20

    12 weeks

  • Fecal Incontinence

    Jorge Wexner Score (Dis Colon Rectum (1993) 36:77) compared to pretreatment * Score for fecal incontinence, with 5 items and score range of 0 - 20

    32 weeks

Secondary Outcomes (6)

  • Fecal Incontinence

    before treatment, 6, 12, 32 wks after initial treatment

  • Anorectal manometric measurements

    12 weeks

  • Quality of Life

    before treatment, 6, 32 wks after initial treatment

  • Cost

    at the end of the treatment

  • Adverse Events

    for each treatment interval

  • +1 more secondary outcomes

Study Arms (1)

pTNS treatment

EXPERIMENTAL
Procedure: Percutaneous tibial nerve stimulation (pTNS)

Interventions

A 34 gauge needle in placed close to the tibial nerve about 2-3 cm above the ankle. A self-adhesive surface electrode is placed on the skin. Needle and surface electrode are connected to an electric stimulator and the stimulating current (0 - 10 mA) is increased in 20 steps. When the patient feels a tingling sensation in the foot, stimulating current is set back for one step and the treatment is started (30 min stimulation).

Also known as: pTNS, peripheral tibial nerve stimulation, peripheral neuromodulation
pTNS treatment

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • fecal urge incontinence
  • conservative treatment has been performed without success

You may not qualify if:

  • current anticoagulation treatment
  • sphincter defects larger than 120°
  • pregnancy
  • pace maker
  • implanted defibrillators
  • severe heart disease
  • existing neurological damages
  • disposition for strong bleeding

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Surgery, Cantonal Hospital St. Gallen

Sankt Gallen, 9007, Switzerland

Location

Related Links

MeSH Terms

Conditions

Fecal Incontinence

Condition Hierarchy (Ancestors)

Rectal DiseasesIntestinal DiseasesGastrointestinal DiseasesDigestive System Diseases

Study Officials

  • Lukas T Marti, Dr. med.

    Department of Surgery, Cantonal Hospital St. Gallen

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Attending physician

Study Record Dates

First Submitted

July 13, 2010

First Posted

July 14, 2010

Study Start

January 1, 2010

Primary Completion

October 1, 2017

Study Completion

December 1, 2017

Last Updated

September 19, 2018

Record last verified: 2018-09

Locations