NCT01162369

Brief Summary

Delirium is an acute confusional state characterized by fluctuating mental status, inattention, and either disorganized thinking or an altered level of consciousness. This form of organ dysfunction occurs in up to 50% of hospitalized patients and is associated with worsening mortality, prolonged hospital length of stay, higher health care costs, and accelerated functional and cognitive decline. Despite the negative consequences of delirium, the majority of cases are unrecognized by hospital physicians because it is not routinely screened for. In an effort to facilitate delirium screening, we sought to validate two brief delirium assessments (\<2 minutes) in the hospital setting.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jul 2013

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 12, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 14, 2010

Completed
3 years until next milestone

Study Start

First participant enrolled

July 1, 2013

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2015

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2016

Completed
Last Updated

May 7, 2018

Status Verified

May 1, 2018

Enrollment Period

2 years

First QC Date

July 12, 2010

Last Update Submit

May 1, 2018

Conditions

Keywords

Delirium, diagnosis, elderly, hospitalization

Outcome Measures

Primary Outcomes (1)

  • B-CAM sensitivity and specificity compared with the psychiatrist reference assessment.

    day of enrollment

Study Arms (2)

Group 1 - Non-Delirius Patients

Group 2 - Delirious Patients

Eligibility Criteria

Age65 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The participants will be those who are Vanderbilt University Hospital inpatients aged 65 years or older. There will be no selection bias in regards to race or gender. Only those who meet the inclusion/exclusion criteria will be considered for study inclusion.

You may qualify if:

  • years of age or greater
  • In the non-ICU inpatient setting
  • Consulted and evaluated by psychiatry

You may not qualify if:

  • Severe mental retardation or dementia
  • Baseline communication barriers such aphasia, deafness, blindness, or who are unable to speak English
  • Refusal of consent
  • Previous enrollment
  • Comatose
  • Out of hospital before the assessments are completed

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Vanderbilt University Hospital

Nashville, Tennessee, 27232, United States

Location

Vanderbilt Emergency Medicine

Nashville, Tennessee, 37232-4700, United States

Location

MeSH Terms

Conditions

DeliriumDisease

Condition Hierarchy (Ancestors)

ConfusionNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsNeurocognitive DisordersMental DisordersPathologic Processes

Study Officials

  • Jin H Han, MD, MSc

    Vanderbilt University Medical Center

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, MSc

Study Record Dates

First Submitted

July 12, 2010

First Posted

July 14, 2010

Study Start

July 1, 2013

Primary Completion

July 1, 2015

Study Completion

July 1, 2016

Last Updated

May 7, 2018

Record last verified: 2018-05

Locations