NCT01154998

Brief Summary

There is a rare condition causing scarring of the lungs termed interstitial lung disease. This comprises a group of conditions which can be divided into separate diseases. The aim of this study is compare a group of patients (the cases) with 2 types of this disease (fibrotic non-specific interstitial pneumonia (NSIP) and idiopathic pulmonary fibrosis (IPF)) with patients without the disease. The study will look at the 2 groups and their exposures to factors such as medications, smoking, previous jobs, previous medical problems and specifically heart disease and any operations or procedures involving the heart. There have been previous studies showing a link between heart disease and scarring of the lungs. This study will look at whether this association is stronger in one or the other type of lung scarring diseases.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
360

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2010

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 30, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

July 1, 2010

Completed
Same day until next milestone

Study Start

First participant enrolled

July 1, 2010

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2011

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2011

Completed
Last Updated

July 1, 2010

Status Verified

June 1, 2010

Enrollment Period

6 months

First QC Date

June 30, 2010

Last Update Submit

June 30, 2010

Conditions

Keywords

non-specific interstitial pneumonia

Study Arms (2)

Cases

Controls

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Cases - patients with IPF or UIP. Controls - hospital clinic attenders.

You may qualify if:

  • idiopathic fibrotic lung disease

You may not qualify if:

  • non idiopathic fibrotic lung disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

St George's Hospital

London, London, SW17 0QT, United Kingdom

Location

MeSH Terms

Conditions

Idiopathic Pulmonary FibrosisLung Diseases, Interstitial

Condition Hierarchy (Ancestors)

Pulmonary FibrosisLung DiseasesRespiratory Tract Diseases

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

June 30, 2010

First Posted

July 1, 2010

Study Start

July 1, 2010

Primary Completion

January 1, 2011

Study Completion

April 1, 2011

Last Updated

July 1, 2010

Record last verified: 2010-06

Locations