NCT01154751

Brief Summary

Long-term, observational, prospective, multicenter registry following patients who have been implanted with the SUPERA Interwoven Self-Expanding Nitinol Stent for treating stenosis in the superficial femoral and/or femoropopliteal arteries.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2008

Longer than P75 for not_applicable

Geographic Reach
1 country

4 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2008

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

June 29, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 1, 2010

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2012

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2015

Completed
2 years until next milestone

Results Posted

Study results publicly available

August 17, 2017

Completed
Last Updated

September 19, 2017

Status Verified

August 1, 2017

Enrollment Period

3.8 years

First QC Date

June 29, 2010

Results QC Date

October 25, 2016

Last Update Submit

August 22, 2017

Conditions

Keywords

Femoral artery stenosisPeripheral vascular Disease

Outcome Measures

Primary Outcomes (4)

  • Six-minute Walking Distance

    The Six-minute Walking Distance test is an objective method for estimation of walking capacity in patients with Peripheral Arterial Disease (PAD) or claudication.

    At baseline

  • Six-minute Walking Distance

    The Six-minute Walking Distance test is an objective method for estimation of walking capacity in patients with Peripheral Arterial Disease (PAD) or claudication.

    30 days

  • Six-minute Walking Distance

    The Six-minute Walking Distance test is an objective method for estimation of walking capacity in patients with Peripheral Arterial Disease (PAD) or claudication.

    6 months

  • Six-minute Walking Distance

    The Six-minute Walking Distance test is an objective method for estimation of walking capacity in patients with Peripheral Arterial Disease (PAD) or claudication.

    1 Year

Secondary Outcomes (16)

  • Number of Participants Experiencing Peri-procedural and Post-procedural Complications

    30 days

  • Number of Peri-procedural and Post-procedural Complications

    30 days

  • Rutherford-Becker Clinical Category

    30 days

  • Restenosis by Duplex Ultrasound

    6 months

  • Restenosis by Duplex Ultrasound

    1 Year

  • +11 more secondary outcomes

Study Arms (1)

Device SUPERA Stent

OTHER

SUPERA Interwoven Self-Expanding Nitinol Stent System

Device: SUPERA Interwoven self-expanding nitinol stent

Interventions

Insertion of stent at stenotic area

Device SUPERA Stent

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may not qualify if:

  • (Clinical)
  • Patient or legal guardian understands registry procedures and has voluntarily signed an informed consent in accordance with institutional and local regulatory policies. (Note: Retrospective data may be collected and entered into the EDC system after a fully executed informed consent has been provided).
  • Rutherford-Becker classification 2 through 5 only
  • Patient is at least 18 years of age and of legal age of consent.
  • Patient must be willing to participate in the registry for at least 5 years.
  • (Angiographic)
  • Target lesion is a single de novo or restenotic (outside a stent) SFA or Popliteal artery lesion ≥ 1 cm from origin of another stent; additional lesions may be present., but there is only one target lesion
  • All SFA target lesions are to be located with the proximal point at least 2 cm below the origin of the profunda femoris artery.
  • All Popliteal Artery target lesions are to be located with the most distal point at least 1 cm proximal to the bifurcation of the anterior tibial artery and the tibioperoneal trunk.
  • Target lesion length 1-20 cm (visual estimate)
  • Target lesion stenosis ≥50% (visual estimate)
  • Popliteal artery patent if the lesion is in the SFA
  • SFA patent if the lesion is in the popliteal artery
  • At least one widely patent (\< 50% stenosis) infrapopliteal artery (for distal run-off)
  • (Clinical)
  • +8 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Herzzentrum Abteilung fur Angiologie

Bad Krozingen, 79189, Germany

Location

Heart Center Leipzig/Park Hospital

Leipzig, 04289, Germany

Location

Kathlisches Klinikum Mainz

Mainz, 55131, Germany

Location

Zentrum fur Diabetes-und GefaBerkrankungen

Münster, 48145, Germany

Location

MeSH Terms

Conditions

Peripheral Arterial DiseasePeripheral Vascular Diseases

Condition Hierarchy (Ancestors)

AtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular Diseases

Results Point of Contact

Title
Margo Zaugg
Organization
Abbott Vascular

Study Officials

  • Thomas Zeller, Prof Dr med

    Herzzentrum Abteilung fur Angiologie, Bad Krozingen, Germany

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
GT60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 29, 2010

First Posted

July 1, 2010

Study Start

November 1, 2008

Primary Completion

August 1, 2012

Study Completion

August 1, 2015

Last Updated

September 19, 2017

Results First Posted

August 17, 2017

Record last verified: 2017-08

Locations