Early Re-Intervention Experiment 2

NCT01153594 | Completed Phase 3 DMC

• 2 other identifiers: ERI-25R37DA011323
• Study Type: interventional
• Target: 446
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study was to evaluate the relative effectiveness of quarterly Recovery Management Checkups (RMC) on long-term outcomes of adult chronic substance users over 4 years.

Conditions

Substance Use Disorders

Keywords

Substance Use Disorders; Relapse; Recovery; Disease Management; Long term outcomes; Addiction Treatment

Outcome Measures

Primary Outcomes (1)

• Time to First Alcohol or Drug Treatment Re-Entry

  Days to readmission was calculated as the number of days from the date of the quarterly follow-up interview where the client first reported being in need of treatment (see below) to the date of the first subsequent intake to alcohol or other drug treatment following that interview.

  Quarterly from random assignment until month 48

Secondary Outcomes (8)

• Any Treatment Re-Entry

  Quarterly from random assignment until month 48

• Times Re-entered Treatment Time Frame

  Quarterly from random assignment until month 48 Description:

• Total Days of Treatment

  Quarterly from random assignment until month 48

• Quarters with 7 days Outpatient or 14 days Residential

  Quarterly from random assignment until month 48

• Quarters Needing Treatment

  Quarterly from random assignment until month 48

Study Arms (2)

Recovery Management Checkups (RMC)

EXPERIMENTAL

Participants in the RMC group are interviewed quarterly. When they were found to be in need of treatment, the participant was transferred from the interviewer to a linkage manager to receive the intervention (described next). They were also able to re-enter treatment on their own and naturally cycle through multiple periods of substance use, treatment, incarceration and recovery.

Behavioral: Recovery Management Checkups (RMC)

Control Group

NO INTERVENTION

Participants in the control group are interviewed quarterly. While they do not receive any active intervention from the research team, they are able to re-enter treatment on their own and naturally cycle through multiple periods of substance use, treatment, incarceration and recovery.

Interventions

Recovery Management Checkups (RMC) BEHAVIORAL

After interviewers completed the quarterly research interview and determined participants' eligibility and need for early re-intervention, they transferred RMC participants who were eligible and in need to a Linkage Manager. Using motivational interviewing, the Linkage Manager: a) provided feedback to participants regarding their current substance use and related problems, b) discussed implications of managing addiction as a chronic condition, c) discussed treatment barriers and solutions, d) assessed and discussed level of motivation for treatment, e) scheduled treatment appointments, f) accompanied participants to treatment intake and stayed through the process, and g) implemented Engagement and Retention Protocol during the 14 days of treatment

Recovery Management Checkups (RMC)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• any substance use in the past 90 days
• any past-year symptoms of substance use disorders.

You may not qualify if:

• under 18
• lived or planned to move outside Chicago within 12 months
• sentenced to a confined environment most of the next 12 months
• mandated to treatment because of a driving under the influence offense
• were not fluent in English or Spanish
• were cognitively unable to provide informed consent.

Sponsors & Collaborators

• Chestnut Health Systems: lead
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (1)

Chestnut Health Systems

Chicago, Illinois, 60610, United States

Location

Related Publications (5)

• Scott CK, Sonis J, Creamer M, Dennis ML. Maximizing follow-up in longitudinal studies of traumatized populations. J Trauma Stress. 2006 Dec;19(6):757-69. doi: 10.1002/jts.20186.

  PMID: 17195975 BACKGROUND

• Dennis M, Scott CK. Managing addiction as a chronic condition. Addict Sci Clin Pract. 2007 Dec;4(1):45-55. doi: 10.1151/ascp074145.

  PMID: 18292710 BACKGROUND

• Rush BR, Dennis ML, Scott CK, Castel S, Funk RR. The interaction of co-occurring mental disorders and recovery management checkups on substance abuse treatment participation and recovery. Eval Rev. 2008 Feb;32(1):7-38. doi: 10.1177/0193841X07307532.

  PMID: 18198169 RESULT

• Scott CK, Dennis ML. Results from two randomized clinical trials evaluating the impact of quarterly recovery management checkups with adult chronic substance users. Addiction. 2009 Jun;104(6):959-71. doi: 10.1111/j.1360-0443.2009.02525.x. Epub 2009 Mar 13.

  PMID: 19344441 RESULT

• McCollister KE, French MT, Freitas DM, Dennis ML, Scott CK, Funk RR. Cost-effectiveness analysis of Recovery Management Checkups (RMC) for adults with chronic substance use disorders: evidence from a 4-year randomized trial. Addiction. 2013 Dec;108(12):2166-74. doi: 10.1111/add.12335. Epub 2013 Oct 9.

  PMID: 23961833 DERIVED

MeSH Terms

Conditions

Substance-Related Disorders; Recurrence

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Michael L Dennis, Ph.D.

  Chestnut Health Systems

  PRINCIPAL INVESTIGATOR

• Christy K Scott, Ph.D.

  Chestnut Health Systems

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 3
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: June 29, 2010
• First Posted: June 30, 2010
• Study Start: February 1, 2004
• Primary Completion: June 1, 2008
• Study Completion: June 1, 2009
• Last Updated: June 30, 2010

Record last verified: 2010-06

Locations

US (1)