NCT01151514

Brief Summary

Few studies analyzed the referral time to nephrologists and its impact on the patient outcome in a large cohort. The investigators described the incidence and determined the outcome with respect to renal function recovery, renal replacement therapy (RRT) requirement and in-hospital mortality of Hospital Acquired Acute Kidney Injury (HA-AKI) without nephrology referral (nrHA-AKI) and late referred HA-AKI patients to nephrologists (lrHA-AKI) compared with early referral patients (erHA-AKI). The patients included were admitted to the tertiary care academic center of Lausanne (Switzerland) between 2004 and 2008, in the medical and surgical services and in the intensive care unit (ICU).

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 23, 2010

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 28, 2010

Completed
Last Updated

June 28, 2010

Status Verified

August 1, 2010

First QC Date

June 23, 2010

Last Update Submit

June 25, 2010

Conditions

Keywords

No referralLate referralAcute kidney injuryIntensive care unitIn-hospital mortalityRenal outcomeRequirement for renal replacement therapyLength of hospital stayImpactIncidence

Outcome Measures

Primary Outcomes (1)

  • Referral patterns for hospital acquired acute kidney injury and relevance to renal outcomes

    Recovery of renal function during hospital stay. Requirement for renal replacement therapy.

Secondary Outcomes (1)

  • Referral patterns for hospital acquired acute kidney injury and relevance to renal outcomes

Study Arms (2)

nrHA-AKI patients

Patients with hospital-acquired acute kidney injury not referred to the nephrologists

Other: Nephrologist referral

lrHA-AKI patients

Patients with hospital-acquired acute kidney injury whao are late referred to the nephrologists

Other: Nephrologist referral

Interventions

Nephrologist specialty, renal replacement therapy

Also known as: Control group: early-referred patients with HA-AKI.
lrHA-AKI patientsnrHA-AKI patients

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

This study population consisted of patients who were hospitalized in the medical and surgical departments as well as in the intensive care untis (ICU) of the University Hospital of Lausanne (Centre Hospitalier Universitaire Vaudois \[CHUV\]) that is a tertiary care academic medical center. Patients with AKI coming from ICU in the medicine or surgery wards, and patients from medicine or surgery wards, who required a transfer to ICU during the hospital stay, were also included whatever the cause of the transfer.

You may qualify if:

  • Adult patients.
  • Hospitalization in the medicine and surgery wards and in the intensive care unit.
  • Hospitalized patients with acquired acute kidney injury according to the
  • Acute Kidney Injury Network (AKIN)criteria.
  • HA-AKI patients with no referral to the nephrologist (nrHA-AKI).
  • HA-AKI patients referred late (more than five days \[\> 5 days\]) to the nephrologist (lrHA-AKI).
  • HA-AKI patients early referred (within five days after sCr increase) to the nephrologist (erHA-AKI).

You may not qualify if:

  • Patients with AKI at the time of the hospital admission and during the first
  • hours after admission.
  • Patients hospitalized in other wards.
  • Children under 18.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nephrology - CHCVs

Sion, 1951, Switzerland

Location

Related Links

MeSH Terms

Conditions

Acute Kidney InjuryTooth, Impacted

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesTooth DiseasesStomatognathic Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

June 23, 2010

First Posted

June 28, 2010

Last Updated

June 28, 2010

Record last verified: 2010-08

Locations