Feasibility of High Frequency QRS Analysis in Patients With Acute Myocardial Infarction
1 other identifier
observational
50
1 country
1
Brief Summary
The primary objective of this study is to characterize the morphological patterns of high frequency QRS components (HFQRS) in patients with acute myocardial infarction (AMI), including STEMI and NSTEMI, compared to patients without AMI.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jun 2010
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2010
CompletedFirst Submitted
Initial submission to the registry
June 10, 2010
CompletedFirst Posted
Study publicly available on registry
June 25, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2011
CompletedFebruary 8, 2011
February 1, 2011
1 year
June 10, 2010
February 6, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Diagnosis of Acute Myocardial Infarction
The primary end-point of the study is diagnosis of acute myocardial infarction, based on cardiac biomarkers, ECG changes clinical symptoms and coronary angiography.
Prior to hospitalization release
Secondary Outcomes (1)
HFQRS analysis for detecting NSTEMI
Post data processing
Study Arms (2)
STEMI
Patients with ST segment elevation myocardial infarction, verified by elevated troponin levels
NSTEMI
Patients with non-ST segment elevation myocardial infarction, verified by elevated levels of troponin
Eligibility Criteria
Patients presenting with confirmed AMI in the intensive cardiac care unit (ICCU) of Soroka Medical Center (Beer Sheva, Israel), who are expected to undergo percutaneous coronary intervention (PCI) will be asked to participate in the study. These include both ST-elevation MI (STEMI) and non ST-elevation MI (NSTEMI) patients, with positive biomarkers and clear ongoing electrocardiographic or clinical evidence of ischemia.
You may qualify if:
- Age \> 40 years (men and women)
- Time from onset of chest pain ≤ 12h
- AMI confirmed by biomarkers
- Clinical or electrocardiographic evidence of ischemia during recording
- Signed an informed consent
You may not qualify if:
- Prior MI
- Prior CABG
- pre-excitation syndrome (e.g. WP)
- Atrial Fibrillation or significant ventricular arrhythmia
- BBB, intraventricular conduction delay or QRS duration \> 120 ms
- Implanted pacemaker or defibrillator
- Left-ventricular hypertrophy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Soroka University Medical Center
Beersheba, 84101, Israel
Related Publications (1)
Amit G, Galante O, Davrath LR, Luria O, Abboud S, Zahger D. High-frequency QRS analysis in patients with acute myocardial infarction: a preliminary study. Ann Noninvasive Electrocardiol. 2013 Mar;18(2):149-56. doi: 10.1111/anec.12023. Epub 2012 Nov 22.
PMID: 23530485DERIVED
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Doron Zahger, MD
Soroka University Medical Center
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- INDUSTRY
Study Record Dates
First Submitted
June 10, 2010
First Posted
June 25, 2010
Study Start
June 1, 2010
Primary Completion
June 1, 2011
Study Completion
June 1, 2011
Last Updated
February 8, 2011
Record last verified: 2011-02