Evaluation of the Sensorial Preference

NCT01146249 | Completed

• 2 other identifiers: P0704012007-A00410-53
• Study Type: observational
• Target: 165
• Locations: 1 country
• Sites: 1

Brief Summary

Among the components of postural control, sensorial integration is of crucial importance. The most important sensorial inputs for postural maintenance are the vestibular system which provides information regarding accelerations of the head in space (HORAK 1994), the somatosensory system which provides proprioceptive information that are used to determine changes in body position (INGLIS 1994) and the visual system which provides information for self motion in the environment. The receptors and the integration channel of each sensorial system have inner characteristics which lead to different performance of the different input in regards to the task and the environmental context (FITZGERALD 1994). Most of time, sensorial information are congruent but sometimes they are conflicted. This is the case when being in a stationary train, the train beside going on, giving the illusory sensation of movement even if the vestibular system is not activated. A sensory weighting process is then necessary for subjects to control balance. The Central Nervous System (CNS) is thought to adjust the relative contribution of sensory input to control stance depending on environmental conditions (CENCIANNI 2006) and the reliability of the sensory input (OIE 2002, KESHNER 2004) in order to maintain or achieve the desired orientation in space and to provide postural stability. Nevertheless the interconnection of the multiple sensorial feedback involved in the postural control is not yet completely understood (CHIARI 2000). Today, there is no tool available to evaluate the individual use of the sensorial information to postural control. It seems interesting to have such a tool to better understand the sensorial preference of subjects. It would be of particular importance for patients with various pathologies in the aim to design individualized balance rehabilitation programs. The aim of the study was to test a tool built to evaluate the sensorial preference of subjects by studying their postural reaction related to the 3 main sensorial perturbations. Normal subjects will be first tested to assess the repeatability of the protocol and to collect normal values. Then, patients with post stroke hemiplegia, vestibular disease, neuropathy and fallers will be studied in order to test the feasibility of the protocol and to have preliminary data of sensorial preference among these populations.

Conditions

Balance

Keywords

Multisensorial integration; Postural control; Visual reliance

Outcome Measures

Primary Outcomes (1)

• Sensory profile before and after rehabilitation

  Sensory profile is defined by change in postural control on force plate under, visual, vestibular, and proprioceptive stimulation.

  at month 1

Secondary Outcomes (15)

• DISEANESS Handicap Inventory scale

  at month 1

• Activities-specific Balance Confidence scale

  at month 1

• Berg Balance scale

  at month 1

• Sensory profile before and after rehabilitation

  at month 6

• Berg Balance scale

  at month 6

Study Arms (5)

1: healthy subject

Other: Balance assessment under sensory stimulation

3: post stroke patients

Other: Balance assessment under sensory stimulation

2: vestibular patients

Vestibular patients with a unique history of peripheric vestibular disorder

Other: Balance assessment under sensory stimulation

4: ataxic patients

Patient with proprioception disorder related to peripheral neuropathy

Other: Balance assessment under sensory stimulation

5: Old fallers

Old subjects with a history of falls (one or more during the last year)

Other: Balance assessment under sensory stimulation

Interventions

Balance assessment under sensory stimulation OTHER

Balance assessment under sensory stimulation

1: healthy subject; 2: vestibular patients; 3: post stroke patients; 4: ataxic patients; 5: Old fallers

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Healthy subjects Vestibular patients Post stroke patients Patient with proprioception disorder Old subjects with a history of falls

You may qualify if:

• Healthy subjects without history of balance disorder
• Vestibular patients with a unique history of peripheric vestibular disorder
• Post stroke patients after a unique hemispheric stroke, being able to stand without any help
• Patient with proprioception disorder related to peripheral neuropathy.
• Old subjects with a history of falls (one or more during the last year).

You may not qualify if:

• For each category, other disorder than the one studied leading to balance trouble.
• Neuropsychological troubles preventing comprehension of the tests.

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead

Study Sites (1)

Service de MPR - Hôpital Lariboisière - Fernand Widal

Paris, 75010, France

Location

Study Officials

• Isabelle BONAN, MD,PhD

  Assistance Publique - Hôpitaux de Paris

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 28, 2010
• First Posted: June 17, 2010
• Study Start: November 26, 2007
• Primary Completion: December 18, 2020
• Study Completion: December 18, 2020
• Last Updated: December 5, 2023

Record last verified: 2023-11

Locations

FR (1)