NCT01140100

Brief Summary

The aim of this study is to determine whether induction of anesthesia with thiopental followed by propofol infusion is able to maintain sufficient depth of anesthesia .

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
82

participants targeted

Target at P50-P75 for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 8, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 9, 2010

Completed
Last Updated

June 9, 2010

Status Verified

January 1, 2007

First QC Date

June 8, 2010

Last Update Submit

June 8, 2010

Conditions

Anesthetics

Study Arms (2)

propofol-propofol

ACTIVE COMPARATOR
Drug: propofol

thiopental-propofol

EXPERIMENTAL
Drug: thiopental,propofol

Interventions

propofolDRUG
propofol-propofol
thiopental,propofolDRUG
thiopental-propofol

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • being adult
  • having ASA I or II
  • scheduled for elective cataract surgery under general anesthesia

You may not qualify if:

  • massive obesity
  • intake of any central nervous system (CNS) stimulants
  • intake of CNS depressants
  • intake of Tricyclic antidepressants
  • known adverse reaction to the study drugs

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shiraz University of Medical Sciences

Shiraz, Fars, Iran

Location

MeSH Terms

Interventions

PropofolThiopental

Intervention Hierarchy (Ancestors)

PhenolsBenzene DerivativesHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbonsOrganic ChemicalsThiobarbituratesBarbituratesPyrimidinonesPyrimidinesHeterocyclic Compounds, 1-RingHeterocyclic Compounds

Study Officials

  • Sina Ghaffaripour, M.D

    Shiraz University of Medical Sciences

    PRINCIPAL INVESTIGATOR

  • Hilda Mahmoudi, M.D

    Shiraz University of Medical Sciences

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

June 8, 2010

First Posted

June 9, 2010

Last Updated

June 9, 2010

Record last verified: 2007-01

Locations

IR(1)