NCT01122654

Brief Summary

This clinical trial will assess growth, tolerance and adverse events of cow milk-based infant formulas in healthy, term infants.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
405

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2010

Geographic Reach
1 country

24 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 10, 2010

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 13, 2010

Completed
2 months until next milestone

Study Start

First participant enrolled

July 1, 2010

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
Last Updated

January 31, 2012

Status Verified

January 1, 2012

Enrollment Period

1.4 years

First QC Date

May 10, 2010

Last Update Submit

January 27, 2012

Conditions

Outcome Measures

Primary Outcomes (1)

  • Body weight measured on calibrated infant scale at each study visit

Secondary Outcomes (5)

  • Twenty-four hour recall of infant formula intake at each study visit

  • Medically-confirmed adverse events collected throughout the study period

  • Twenty-four hour recall of stool characteristics (number and consistency) and tolerance at each study visit

  • Parental Product Assessment Questionnaire completed at Study Visit 2

  • Body Length and Head Circumference measured at each study visit

Study Arms (3)

Control

Experimental 1

Experimental 2

Eligibility Criteria

Age12 Days - 16 Days
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

Healthy, term infants

You may qualify if:

  • Singleton, 12-16 days of age at randomization
  • Term infant with birth weight of minimum of 2500 g
  • Solely formula fed
  • Signed Informed Consent and Protected Health Information

You may not qualify if:

  • History of underlying metabolic or chronic disease or immunocompromised
  • Acute infection
  • Feeding difficulties or formula intolerance

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (24)

Birmingham Pediatric Associates

Birmingham, Alabama, 35205, United States

Location

Southeastern Pediatric Associates

Dothan, Alabama, 36305, United States

Location

Pediatrics East - Alabama Clinical Therapeutics

Pinson, Alabama, 35126, United States

Location

Central Arkansas Pediatric Clinic

Benton, Arkansas, 72019, United States

Location

Arkansas Pediatric Clinic

Little Rock, Arkansas, 72205, United States

Location

Norwich Pediatric Group, PC

Norwich, Connecticut, 06360, United States

Location

Altamonte Pediatric Associates

Lake Mary, Florida, 32746, United States

Location

Children's Medical Association

Plantation, Florida, 33324, United States

Location

North Georgia Clinical Research Center/White's Pediatrics

Dalton, Georgia, 30721, United States

Location

Deaconess Clinic Gateway

Newburgh, Indiana, 47630, United States

Location

PTCU/Children & Youth Project

Louisville, Kentucky, 40202, United States

Location

Owensboro Pediatrics

Owensboro, Kentucky, 42303, United States

Location

Woburn Pediatric Associates

Woburn, Massachusetts, 01801, United States

Location

Southwestern Medical Clinic, PC

Niles, Michigan, 49120, United States

Location

Southwestern Medical Clinic P.C.

Stevensville, Michigan, 49127, United States

Location

The Center for Human Nutrition

Omaha, Nebraska, 68105, United States

Location

Cary Pediatric Center, PA

Cary, North Carolina, 27511, United States

Location

Innovis Health South University

Fargo, North Dakota, 58103, United States

Location

Red Lion Pediatrics

Philadelphia, Pennsylvania, 19114, United States

Location

Primary Physicians Research, Inc

Pittsburgh, Pennsylvania, 15241, United States

Location

Alpha Clinical Research

Clarksville, Tennessee, 37043, United States

Location

The Jackson Clinic - North Jackson

Jackson, Tennessee, 38305, United States

Location

Holston Medical Group

Kingsport, Tennessee, 37660, United States

Location

Austin Diagnostic Clinic

Austin, Texas, 78745, United States

Location

Related Publications (1)

  • Johnston WH, Ashley C, Yeiser M, Harris CL, Stolz SI, Wampler JL, Wittke A, Cooper TR. Growth and tolerance of formula with lactoferrin in infants through one year of age: double-blind, randomized, controlled trial. BMC Pediatr. 2015 Nov 7;15:173. doi: 10.1186/s12887-015-0488-3.

MeSH Terms

Conditions

Body Weight

Condition Hierarchy (Ancestors)

Signs and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

May 10, 2010

First Posted

May 13, 2010

Study Start

July 1, 2010

Primary Completion

December 1, 2011

Study Completion

December 1, 2011

Last Updated

January 31, 2012

Record last verified: 2012-01

Locations