The Effect of Gabapentin (Neurentin) and Pregabalin (Lyrica) in Pain Reduction After Photorefractive Keratectomy
PRK
1 other identifier
interventional
N/A
1 country
1
Brief Summary
The studied patients will be given randomly one of three following drugs1:Gabapentin2: Pregabalin or placebo for 3 days after Photorefractive keratectomy surgery. The pain will be measured based on visual analog scale(VAS) on the day of operation and on the 3 rd day (morning, evening) and then compared among three groups.
Trial Health
Trial Health Score
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1 active site
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Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 12, 2010
CompletedFirst Posted
Study publicly available on registry
May 12, 2010
CompletedMay 12, 2010
March 1, 2010
April 12, 2010
May 10, 2010
Conditions
Outcome Measures
Primary Outcomes (1)
pain degree based on visual analog scale(VAS)
Study Arms (2)
Gabapentin
ACTIVE COMPARATORPregabalin
ACTIVE COMPARATORInterventions
Eligibility Criteria
You may qualify if:
- patients candidate for PRK, 17\<age\<70
You may not qualify if:
- use of any systemic analgesic drugs, drug intolerance, need of systemic or topical administration of NSAIDs or eye drops for allergy and glaucoma, dry eyes, pregnancy, breast feeding
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Ophthalmic Research Center
Tehran, Tehran Province, 166666, Iran
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Purpose
- TREATMENT
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
April 12, 2010
First Posted
May 12, 2010
Last Updated
May 12, 2010
Record last verified: 2010-03