CPR Rescuer Fatigue on Chest Compression Effectiveness

NCT01117896 | Completed

• 1 other identifier: 2007-5-5367
• Study Type: interventional
• Target: 106
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective, randomized experimental trial to determine whether the quality of healthcare provider/rescuer chest compressions (CC) deteriorates at the same rate in pediatric models as compared to adult models. To determine the relationship between physiologic/metabolic markers of work in rescuers and chest compression deterioration, and to determine the effect of stepstool use on the quality of chest compressions and metabolic demand. To determine whether the quality of chest compressions deteriorates at the same rate in participants using a stepstool compared to those not using a stepstool.

Conditions

Rescuer Fatigue During CPR

Keywords

CPR; Rescuer fatigue; Chest Compression effectiveness

Outcome Measures

Primary Outcomes (3)

• Compression Quality

  The primary endpoint will be the difference in mean number of effective compressions per minute in each manikin at times 1, 2, 5 and 10 minutes.

  2 years

• Metabolic expenditure

  The endpoint will be the difference between mean time to ineffective compressions (defined as 10 consecutive compressions that fail to meet AHA guidelines for depth and rate) and mean time to anaerobic threshold in each manikin.

  2 years

• Effect of Step stool use

  The endpoint will be the difference between mean time to ineffective compressions (defined as 10 consecutive compressions that fail to meet AHA guidelines for depth and rate) and mean time to anaerobic threshold in each experimental group.

  3 years

Secondary Outcomes (4)

• Visual Analogue Scale (VAS) Score

  3 years

• Physiologic measures and CC quality

  3 years

• Effect of stepstool use on duration of effective compressions.

  3 yrs

• • Correlation of subjective reviewer rating and quantitative objective chest compression quality.

  3 years

Study Arms (2)

Adult vs Pedi manikin CC quality

EXPERIMENTAL

The primary objective is to determine whether chest compression deterioration occurs at the same rate in pediatric and adult manikins. The primary endpoint will be the difference in mean number of effective compressions per minute in each manikin at times 1, 2, 5 and 10 minutes. Another objective is to identify the correlation between the anaerobic threshold and the deterioration of compressions in each manikin. The endpoint will be the difference between mean time to ineffective compressions (defined as 10 consecutive compressions that fail to meet AHA guidelines for depth and rate) and mean time to anaerobic threshold in each manikin.

Other: Chest compression on adult and pedi manikins

Stepstool use

EXPERIMENTAL

A third main objective is to determine the effect of the stepstool use on the quality of chest compressions and metabolic demand. The endpoint will be the difference between mean time to ineffective compressions (defined as 10 consecutive compressions that fail to meet AHA guidelines for depth and rate) and mean time to anaerobic threshold in each experimental group.

Other: Use of stepstool during chest compressions

Interventions

Chest compression on adult and pedi manikins OTHER

Each participant will be required to perform chest compressions on all 2 manikins, one on each of 2 assigned days. Participants will be randomized to one of 2 groups differing only in the order of manikins compressed, i.e. pediatric-adult; adult-pediatric, etc.

Also known as: chest compression on adult manikins, chest compression on pedi manikins

Adult vs Pedi manikin CC quality

Use of stepstool during chest compressions OTHER

In the additional arm of the study, a new cohort of participants will use only the adult manikin on two separate sessions. Participants will be randomized to one of two groups differing only in the use of a stepstool.

Also known as: chest compression adult manikin

Stepstool use

Eligibility Criteria

• Age: 22 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Males or females age 22 to 65 years.
• Resident physicians, fellows, attendings, nurses and emergency medical technicians (EMTs) who routinely perform chest compressions in the Critical Care units and Emergency Department.

You may not qualify if:

• Lay practitioners
• Pregnant women
• Chronic medical Condition limiting exertional capacity

Sponsors & Collaborators

• Children's Hospital of Philadelphia: lead

Study Sites (1)

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States

Location

Related Publications (1)

• Badaki-Makun O, Nadel F, Donoghue A, McBride M, Niles D, Seacrist T, Maltese M, Zhang X, Paridon S, Nadkarni VM. Chest compression quality over time in pediatric resuscitations. Pediatrics. 2013 Mar;131(3):e797-804. doi: 10.1542/peds.2012-1892. Epub 2013 Feb 25.

  PMID: 23439892 DERIVED

Study Officials

• Fran Nadel, MD

  Children's Hospital of Philadelphia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 4, 2010
• First Posted: May 6, 2010
• Study Start: May 1, 2007
• Primary Completion: August 1, 2008
• Study Completion: July 1, 2012
• Last Updated: October 26, 2012

Record last verified: 2012-10

Locations

US (1)